valdecoxib, Bextra (cont.)
Omudhome Ogbru, PharmD
Omudhome Ogbru, PharmD
Dr. Ogbru received his Doctorate in Pharmacy from the University of the Pacific School of Pharmacy in 1995. He completed a Pharmacy Practice Residency at the University of Arizona/University Medical Center in 1996. He was a Professor of Pharmacy Practice and a Regional Clerkship Coordinator for the University of the Pacific School of Pharmacy from 1996-99.
Medical and Pharmacy Editor:
GENERIC AVAILABLE: No
PREPARATIONS: Oblong white tablets containing 10 or 20mg of valdecoxib.
STORAGE: Valdecoxib tablets should be stored at room temperature, 59-86 °F (15-30 °C).
PRESCRIBED FOR: Valdecoxib is used for the relief of pain, fever, swelling, and tenderness caused by osteoarthritis and rheumatoid arthritis, but it does not prevent the destruction of joints by the arthritis. Valdecoxib also is approved for the relief of pain of menstrual cramps (primary dysmenorrhea).
DOSING: For osteoarthritis or rheumatoid arthritis, the usual approved dose of valdecoxib is 10 mg once daily. For dysmenorrhea, the dose is 20 mg twice daily. Valdecoxib may be taken with or without food.
PREGNANCY: In pregnant animals, valdecoxib has been shown to cause fetal abnormalities. Although the use of valdecoxib by pregnant women has not been studied carefully, fetal abnormalities have been reported in women who took valdecoxib during pregnancy. Valdecoxib should be used during pregnancy only if the potential benefit justifies the potential risk to the fetus. Valdecoxib should be avoided during late pregnancy. Valdecoxib should be used during pregnancy only if the potential benefit justifies the potential risk to the fetus. Valdecoxib should be avoided during late pregnancy.
NURSING MOTHERS: The use of valdecoxib in nursing mothers has not been evaluated.
SIDE EFFECTS: The most common side effects of valdecoxib are headache, abdominal pain, diarrhea, nausea, flatulence and insomnia. Other side effects include fainting, kidney failure, heart failure, fluid retention, aggravation of hypertension, chest pain, ringing in the ears, deafness, stomach and intestinal ulcers, bleeding, blurred vision, anxiety, photosensitivity, weight gain, water retention, flu-like symptoms, drowsiness and weakness.
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