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February 9, 2012

Vaginal Cancer

What is vaginal cancer?

Vaginal cancer is a disease in which malignant (cancer) cells form in the vagina.

The vagina is the canal leading from the cervix (the opening of uterus) to the outside of the body. At birth, a baby passes out of the body through the vagina (also called the birth canal).

Vaginal cancer is not common. When found in early stages, it can often be cured. There are two main types of vaginal cancer:

  • Squamous cell carcinoma: Cancer that forms in squamous cells, the thin, flat cells lining the vagina. Squamous cell vaginal cancer spreads slowly and usually stays near the vagina, but may spread to the lungs and liver. This is the most common type of vaginal cancer. It is found most often in women aged 60 or older.


  • Adenocarcinoma: Cancer that begins in glandular (secretory) cells. Glandular cells in the lining of the vagina make and release fluids such as mucus. Adenocarcinoma is more likely than squamous cell cancer to spread to the lungs and lymph nodes. It is found most often in women aged 30 or younger.

What are causes and risk factors for vaginal cancer?

Age and exposure to the drug DES (diethylstilbestrol) before birth affect a woman's risk of developing vaginal cancer.

Anything that increases your risk of getting a disease is called a risk factor. Risk factors for vaginal cancer include the following:

  • Being aged 60 or older.


  • Being exposed to DES while in the mother's womb. In the 1950s, the drug DES was given to some pregnant women to prevent miscarriage (premature birth of a fetus that cannot survive). Women who were exposed to DES before birth have an increased risk of developing vaginal cancer. Some of these women develop a rare form of cancer called clear cell adenocarcinoma.


  • Having human papilloma virus (HPV) infection.


  • Having a history of abnormal cells in the cervix or cervical cancer.




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Vaginal Cancer

Cervical cancer facts

  • Causes and risk factors for cervical cancer have been identified and include human papillomavirus (HPV) infection, having many sexual partners, smoking, taking birth control pills, and engaging in early sexual contact.
  • HPV infection may cause cervical dysplasia, or abnormal growth of cervical cells.
  • Regular pelvic exams and Pap testing can detect precancerous changes in the cervix.
  • Precancerous changes in the cervix may be treated with cryosurgery, cauterization, or laser surgery.
  • The most common symptoms and signs of cervical cancer are abnormal bleeding and pelvic pain.
  • Cervical cancer can be diagnosed using a Pap smear or other procedures that sample the cervix tissue.
  • Chest X-rays, CT scan, MRI, and a PET scan may be used to determine the stage of cervical cancer.
  • Cancer of the cervix requires different treatment than cancer that begins in other parts of ...

Read the Cervical Cancer article »







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