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- What is ursodiol, and how does it work (mechanism of action)?
- What brand names are available for ursodiol?
- Do I need a prescription for ursodiol?
- What are the side effects of ursodiol?
- What is the dosage for ursodiol?
- Which drugs or supplements interact with ursodiol?
- Is ursodiol safe to take if I'm pregnant or breastfeeding?
- What else should I know about ursodiol?
What is ursodiol, and how does it work (mechanism of action)?
Ursodiol is a naturally-occurring bile acid that is made by the liver in humans and is secreted in small quantities into bile. It is used to dissolve and prevent cholesterol gallstones and to treat primary biliary cirrhosis, a disease of the liver. Ursodiol blocks the enzyme in the liver that produces cholesterol and thereby decreases production of cholesterol by the liver and the amount of cholesterol in bile. It also reduces the absorption of cholesterol from the intestine. By decreasing the concentration of cholesterol in bile, ursodiol prevents the formation and promotes the dissolution of cholesterol-containing gallstones. The mechanism by which it acts in primary biliary cirrhosis is not clear. The FDA approved ursodiol in December 1987.
What brand names are available for ursodiol?
Actigall, Urso Forte, Urso 250
Do I need a prescription for ursodiol?
What are the side effects of ursodiol?
The most common side effects are:
Serious allergic reactions and reduced concentration of white blood cells also have occurred.
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