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urokinase-injection, Abbokinase

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GENERIC NAME: UROKINASE - INJECTION (you-row-KYE-naze)

BRAND NAME(S): Abbokinase

Warning | Medication Uses | How To Use | Side Effects | Precautions | Drug Interactions | Overdose | Notes | Missed Dose | Storage

WARNING: Internal bleeding may be more difficult to control with this medication than with other anticoagulant therapy. This medication must be used in a hospital setting. It should be started as soon as possible after lung blood clots have been noticed (pulmonary embolism), preferably within 7 days. Urokinase should be given within 6 hours of the first symptoms of a heart attack associated with evolving myocardial infarction.

USES: This medication is a protein (enzyme) which works to break up and dissolve blood clots which can block arteries. It is used in the treatment of very serious blood clots in lung blood vessels (pulmonary embolism).

HOW TO USE: This medication is given by injection by a health care professional. It is important this medication be used as prescribed. It is most effective when administered as soon as possible after symptoms appear (e.g., within 6 hours of onset of chest pain).

SIDE EFFECTS: Dizziness, fever, headache, or nausea may occur shortly after the drug is given by vein (infusion reaction). Notify the doctor immediately if any of these effects occur, as the drug infusion may need to be stopped, or medication to treat the reaction may need to be given. Notify your doctor immediately if you experience: easy bruising or bleeding (e.g., pink urine, bleeding gums, black or bloody stools), a rapid or abnormal heartbeat, chest pain, tingling or numbness of the hands/feet. An allergic reaction to this drug is unlikely, but seek immediate medical attention if it occurs. Symptoms of an allergic reaction include: rash, itching, swelling, severe dizziness, trouble breathing. Rare (possibly fatal) cholesterol blood clots (emboli) may occur while using medicines that dissolve blood clots. Report immediately any of the following symptoms: change in amount of urine, severe stomach/abdominal pain, unexplained muscle pain, discolored toes or fingers. If you notice other effects not listed above, contact your doctor or pharmacist.

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