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 Tuberculosis Skin Test (PPD Skin Test) Main Article |  Glossary |  Tuberculosis Skin Test (PPD Skin Test) Index 

Tuberculosis Skin Test (PPD Skin Test) Glossary of Terms

The following are health and medical definitions of terms that appear in the Tuberculosis Skin Test (PPD Skin Test) article.

Arthritis: Inflammation of a joint. When joints are inflamed they can develop stiffness, warmth, swelling, redness and pain. There are over 100 types of arthritis. (see osteoarthritis, rheumatoid arthritis, ankylosing spondylitis, psoriatic arthritis, lupus, gout, pseudogout).

Axis: The axis is the second cervical vertebra (symbol: C2). It is called the "axis" because the uppermost cervical vertebra (called the atlas) rotates about the odontoid process of C2. The joint between the axis and atlas is a pivot type of joint. It allows the head turn.
See the entire definition of Axis

Bacterium: The singular of bacteria.

Bleb: A bladder-like structure more than 5 mm in diameter with thin walls that may be full of fluid. Also called a bulla.
See the entire definition of Bleb

Crohn's disease : A chronic inflammatory disease, primarily involving the small and large intestine, but which can affect other parts of the digestive system as well. It is named for Burrill Crohn, the American gastroenterologist who first described the disease in 1932.
See the entire definition of Crohn's disease

Culture: A culture is the propagation of microorganisms in a growth media. Any body tissue or fluid can be evaluated in the laboratory by culture techniques in order to detect and identify infectious processes. Culture techniques also be used to determine sensitivity to antibiotics.

Diabetes: Refers to diabetes mellitus or, less often, to diabetes insipidus . Diabetes mellitus and diabetes insipidus share the name "diabetes" because they are both conditions characterized by excessive urination (polyuria).
See the entire definition of Diabetes

Disease: Illness or sickness often characterized by typical patient problems (symptoms) and physical findings (signs). Disruption sequence: The events that occur when a fetus that is developing normally is subjected to a destructive agent such as the rubella (German measles) virus.

Edema: The swelling of soft tissues as a result of excess water accumulation.
See the entire definition of Edema

Fibrin: The protein formed during normal blood clotting that is the essence of the clot.

Forearm: The portion of the upper limb from the elbow to the wrist.
See the entire definition of Forearm

Immune: Protected against infection. The Latin immunis means free, exempt.

Immune response: Any reaction by the immune system.

Immune system: A complex system that is responsible for distinguishing us from everything foreign to us, and for protecting us against infections and foreign substances. The immune system works to seek and kill invaders.
See the entire definition of Immune system

Immunocompromised: Having an immune system that has been impaired by disease or treatment.
See the entire definition of Immunocompromised back to top

Induration : Localized hardening of soft tissue of the body. The area becomes firm, but not as hard as bone .
See the entire definition of Induration

Infection: The growth of a parasitic organism within the body. (A parasitic organism is one that lives on or in another organism and draws its nourishment therefrom.) A person with an infection has another organism (a "germ") growing within him, drawing its nourishment from the person.
See the entire definition of Infection

Kidney: One of a pair of organs located in the right and left side of the abdomen which clear "poisons" from the blood, regulate acid concentration and maintain water balance in the body by excreting urine. The kidneys are part of the urinary tract. The urine then passes through connecting tubes called "ureters" into the bladder. The bladder stores the urine until it is released during urination.


See the entire definition of Kidney

Palpable: Something that can be felt or touched. For example, a palpable tumor is one that can be felt. From the Latin "palpare" (to stroke or to pat).
See the entire definition of Palpable

PPD: 1. Postpartum depression. 2. Purified protein derivative (the PPD skin test for tuberculosis).

Protein: A large molecule composed of one or more chains of amino acids in a specific order determined by the base sequence of nucleotides in the DNA coding for the protein.
See the entire definition of Protein

Rheumatoid arthritis : An autoimmune disease which causes chronic inflammation of the joints, the tissue around the joints, as well as other organs in the body. Autoimmune diseases occur when the body tissues are mistakenly attacked by its own immune system. The immune system is a complex organization of cells and antibodies designed normally to "seek and destroy" invaders of the body, particularly infections. Patients with these diseases have antibodies in their blood which target their own body tissues, where they can be associated with inflammation. Because it can affect multiple other organs of the body, rheumatoid arthritis is referred to as a systemic illness and is sometimes called rheumatoid disease. While rheumatoid arthritis is a chronic illness (meaning it can last for years) patients may experience long periods without symptoms.
See the entire definition of Rheumatoid arthritis

Skin: The skin is the body's outer covering. It protects us against heat and light, injury, and infection. It regulates body temperature and stores water, fat, and vitamin D. Weighing about 6 pounds, the skin is the body's largest organ. It is made up of two main layers; the outer epidermis and the inner dermis.


See the entire definition of Skin

Syringe: A device used in medicine to inject fluid into or withdraw fluid from the body. Medical syringes consist of a needle attached to a hollow cylinder that is fitted with a sliding plunger. The downward movement of the plunger injects fluid; upward movement withdraws fluid.
See the entire definition of Syringe

Tuberculin: A protein extracted from Mycobacterium tuberculosis that is used in a skin test to determine if a person has been exposed to tuberculosis. The tuberculin preparation in most common use today is purified protein derivative (PPD) tuberculin. PPD is injected (or multiple-punctured) into the skin. If a reaction is seen at and around the site of injection, the test is positive. The PPD tuberculin test done by intradermal injection is also known as the Mantoux test.

Tuberculosis : A highly contagious infection caused by the bacterium called Mycobacterium tuberculosis. Abbreviated TB. Tubercles (tiny lumps) are a characteristic finding in TB. Diagnosis may be made by skin test, which if positive should will be followed by a chest X-ray to determine the status (active or dormant) of the infection. Tuberculosis is more common in people with immune system problems, such as AIDS, than in the general population. Treatment of active tuberculosis is mandatory by law in the US, and should be available at no cost to the patient through the public health system. It involves a course of antibiotics and vitamins that lasts about six months. It is important to finish the entire treatment, both to prevent reoccurrence and to prevent the development of antibiotic-resistant tuberculosis. Most patients with tuberculosis do not need to be quarantined, but it is sometimes necessary.
See the entire definition of Tuberculosis

Vasodilation: Widening of blood vessels resulting from relaxation of the muscular wall of the vessels. What widens is actually the diameter of the interior (the lumen) of the vessel. The opposite of vasoconstriction.

Wheal: A raised, itchy (pruritic) area of skin that is almost always an overt sign of allergy .
See the entire definition of Wheal back to top

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