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February 10, 2012

Tuberculosis Skin Test (PPD Skin Test) Glossary of Terms

The following are health and medical definitions of terms that appear in the Tuberculosis Skin Test (PPD Skin Test) article.

Arthritis: Inflammation of a joint. When joints are inflamed they can develop stiffness, warmth, swelling, redness and pain. There are over 100 types of arthritis. (see osteoarthritis, rheumatoid arthritis, ankylosing spondylitis, psoriatic arthritis, lupus, gout, pseudogout).

Bacteria: Single-celled microorganisms which can exist either as independent (free-living) organisms or as parasites (dependent upon another organism for life).
See the entire definition of Bacteria

Bacterium: The singular of bacteria.

BCG: An effective immunization against tuberculosis. BCG stands for Bacille Calmette Guerin. BCG is a weakened (attenuated) version of a bacteria called Mycobacterium bovis which is closely related to Mycobacterium tuberculosis, the agent responsible for tuberculosis.
See the entire definition of BCG

Cancer: An abnormal growth of cells which tend to proliferate in an uncontrolled way and, in some cases, to metastasize (spread).
See the entire definition of Cancer

Chemotherapy: 1. In the original sense, a chemical that binds to and specifically kills microbes or tumor cells. The term chemotherapy was coined in this regard by Paul Ehrlich (1854-1915).
2. In oncology, drug therapy for cancer. Also called "chemo" for short.
See the entire definition of Chemotherapy

Chronic: This important term in medicine comes from the Greek chronos, time and means lasting a long time.
See the entire definition of Chronic

Diabetes: Refers to diabetes mellitus or, less often, to diabetes insipidus. Diabetes mellitus and diabetes insipidus share the name "diabetes" because they are both conditions characterized by excessive urination (polyuria).
See the entire definition of Diabetes

Edema: The swelling of soft tissues as a result of excess water accumulation.
See the entire definition of Edema

False negative: A result that appears negative but fails to reveal a situation. An example of a false negative: a particular test designed to detect cancer of the toenail is negative but the person has toenail cancer.

False positive: A result that is erroneously positive when a situation is normal. An example of a false positive: a particular test designed to detect cancer of the toenail is positive but the person does not have toenail cancer.

Fibrin: The protein formed during normal blood clotting that is the essence of the clot.

Forearm: The portion of the upper limb from the elbow to the wrist.
See the entire definition of Forearm

Immune: Protected against infection. The Latin immunis means free, exempt.

Immune response: Any reaction by the immune system.

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Immune system: A complex system that is responsible for distinguishing us from everything foreign to us, and for protecting us against infections and foreign substances. The immune system works to seek and kill invaders.
See the entire definition of Immune system

Immunocompromised: Having an immune system that has been impaired by disease or treatment.

Incubation period: In medicine, the time from the moment of exposure to an infectious agent until signs and symptoms of the disease appear. For example, the incubation period of chickenpox is 14-16 days.
See the entire definition of Incubation period

Induration: Localized hardening of soft tissue of the body. The area becomes firm, but not as hard as bone.

Infection: The growth of a parasitic organism within the body. (A parasitic organism is one that lives on or in another organism and draws its nourishment therefrom.) A person with an infection has another organism (a "germ") growing within him, drawing its nourishment from the person.
See the entire definition of Infection

Kidney: One of a pair of organs located in the right and left side of the abdomen which clear "poisons" from the blood, regulate acid concentration and maintain water balance in the body by excreting urine. The kidneys are part of the urinary tract. The urine then passes through connecting tubes called "ureters" into the bladder. The bladder stores the urine until it is released during urination.


See the entire definition of Kidney

Latent: Hidden, dormant, inactive.
See the entire definition of Latent

Lungs: The lungs are a pair of breathing organs located with the chest which remove carbon dioxide from and bring oxygen to the blood. There is a right and left lung.

Mantoux test: A skin test for tuberculosis, named for the French physician Charles Mantoux (1877-1947). See: Tuberculin.

Nutrition: 1) The science or practice of taking in and utilizing foods. 2) A nourishing substance, such as nutritional solutions delivered to hospitalized patients via an IV or IG tube.

Palpable: Something that can be felt or touched. For example, a palpable tumor is one that can be felt. From the Latin "palpare" (to stroke or to pat).

PPD: 1. Postpartum depression. 2. Purified protein derivative (the PPD skin test for tuberculosis).

Pregnant: The state of carrying a developing fetus within the body.
See the entire definition of Pregnant

Protein: A large molecule composed of one or more chains of amino acids in a specific order determined by the base sequence of nucleotides in the DNA coding for the protein.
See the entire definition of Protein

Rheumatoid arthritis: An autoimmune disease which causes chronic inflammation of the joints, the tissue around the joints, as well as other organs in the body. Autoimmune diseases occur when the body tissues are mistakenly attacked by its own immune system. The immune system is a complex organization of cells and antibodies designed normally to "seek and destroy" invaders of the body, particularly infections. Patients with these diseases have antibodies in their blood which target their own body tissues, where they can be associated with inflammation. Because it can affect multiple other organs of the body, rheumatoid arthritis is referred to as a systemic illness and is sometimes called rheumatoid disease. While rheumatoid arthritis is a chronic illness (meaning it can last for years) patients may experience long periods without symptoms.
See the entire definition of Rheumatoid arthritis back to top

Steroid: A general class of chemical substances that are structurally related to one another and share the same chemical skeleton (a tetracyclic cyclopenta[a]phenanthrene skeleton).
See the entire definition of Steroid

Syringe: A device used in medicine to inject fluid into or withdraw fluid from the body. Medical syringes consist of a needle attached to a hollow cylinder that is fitted with a sliding plunger. The downward movement of the plunger injects fluid; upward movement withdraws fluid.
See the entire definition of Syringe

Therapy: The treatment of disease.
See the entire definition of Therapy

Tuberculin: A protein extracted from Mycobacterium tuberculosis that is used in a skin test to determine if a person has been exposed to tuberculosis. The tuberculin preparation in most common use today is purified protein derivative (PPD) tuberculin. PPD is injected (or multiple-punctured) into the skin. If a reaction is seen at and around the site of injection, the test is positive. The PPD tuberculin test done by intradermal injection is also known as the Mantoux test.

Tuberculosis: A highly contagious infection caused by the bacterium called Mycobacterium tuberculosis. Abbreviated TB. Tubercles (tiny lumps) are a characteristic finding in TB. Diagnosis may be made by skin test, which if positive should will be followed by a chest X-ray to determine the status (active or dormant) of the infection. Tuberculosis is more common in people with immune system problems, such as AIDS, than in the general population. Treatment of active tuberculosis is mandatory by law in the US, and should be available at no cost to the patient through the public health system. It involves a course of antibiotics and vitamins that lasts about six months. It is important to finish the entire treatment, both to prevent reoccurrence and to prevent the development of antibiotic-resistant tuberculosis. Most patients with tuberculosis do not need to be quarantined, but it is sometimes necessary.
See the entire definition of Tuberculosis

Vasodilation: Widening of blood vessels resulting from relaxation of the muscular wall of the vessels. What widens is actually the diameter of the interior (the lumen) of the vessel. The opposite of vasoconstriction.

Viral: Of or pertaining to a virus. For example, "My daughter has a viral rash."

Viral infection: Infection caused by the presence of a virus in the body. Depending on the virus and the person's state of health, various viruses can infect almost any type of body tissue, from the brain to the skin. Viral infections cannot be treated with antibiotics; in fact, in some cases the use of antibiotics makes the infection worse. The vast majority of human viral infections can be effectively fought by the body's own immune system, with a little help in the form of proper diet, hydration, and rest. As for the rest, treatment depends on the type and location of the virus, and may include anti-viral or other drugs.

Wheal: A raised, itchy (pruritic) area of skin that is almost always an overt sign of allergy.
See the entire definition of Wheal

World Health Organization: An agency of the United Nations established in 1948 to further international cooperation in improving health conditions. Although the World Health Organization inherited specific tasks relating to epidemic control, quarantine measures, and drug standardization from the Health Organization of the League of Nations (that was set up in 1923) and from the International Office of Public Health at Paris (established in 1909), the World Health Organization was given a broad mandate under its constitution to promote the attainment of "the highest possible level of health" by all people. WHO defines health positively as "a state of complete physical, mental, and social well-being and not merely the absence of disease or infirmity."
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Suggested Reading on Tuberculosis Skin Test (PPD Skin Test) by Our Doctors

  • Related Diseases & Conditions

    • Crohn's Disease
      • Crohn's disease is a chronic inflammatory disease, primarily involving the small and large intestine, but which can affect other parts of the digestive system as well. Abdominal pain, diarrhea, vomiting, fever, and weight loss are common symptoms.
    • Rheumatoid Arthritis
      • Rheumatoid arthritis is an autoimmune disease that causes chronic inflammation of the joints, the tissue around the joints, as well as other organs in the body. Because it can affect multiple other organs of the body, rheumatoid arthritis is referred to as a systemic illness and is sometimes called rheumatoid disease.
    • Diabetes (Type 1 and Type 2)
      • Diabetes mellitus is a chronic condition characterized by high levels of sugar (glucose) in the blood. The two types of diabetes are referred to as type 1 (insulin dependent) and type 2 (non-insulin dependent). Symptoms of diabetes include increased urine output, thirst, hunger, and fatigue. Treatment of diabetes depends on the type.
    • Tuberculosis
      • Tuberculosis (TB) is an infectious disease caused by Mycobacterium tuberculosis bacteria. Symptoms include weakness, fever, weight loss, night sweats and in worse cases, chest pain, shortness of breath, and coughing up blood. A person with an active infection (a positive TB skin test, abnormal chest x-ray and TB bacteria in their sputum) requires treatment with izoniazid, rifampin, ethambutol and pyrazinaide.
    • Cancer
      • Cancer is a disease caused by an abnormal growth of cells, also called malignancy. It is a group of 100 different diseases, and is not contagious. Cancer can be treated through chemotherapy, a treatment of drugs that destroy cancer cells.
    • Hypertensive Kidney Disease
      • High blood pressure can damage the kidneys and is one of the leading causes of kidney failure (end-stage renal kidney disease). Kidney damage, like hypertension, can be unnoticeable and detected only through medical tests. If you have kidney disease, you should control your blood pressure. Other treatment options include prescription medications.
    • Extensively Drug-Resistant Tuberculosis (XDR TB)
      • Extensively drug-resistant tuberculosis (XDR TB) is a rare form of multidrug-resistant tuberculosis (MDR TB) that's transmitted when TB germs are expelled into the air by sneezing, speaking, singing, or coughing.
    • Disease Prevention in Women
      • Disease prevention in women includes screening tests that are a basic part of prevention medicine. All screening tests are commonly available through your general doctor. Some specialized tests may be available elsewhere.
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Tuberculosis Skin Test (PPD Skin Test)

Diabetes Facts

  • Diabetes is a chronic condition associated with abnormally high levels of sugar (glucose) in the blood.
  • Insulin produced by the pancreas lowers blood glucose.
  • Absence or insufficient production of insulin causes diabetes.
  • The two types of diabetes are referred to as type 1 (insulin dependent) and type 2 (non-insulin dependent).
  • Symptoms of diabetes include increased urine output, thirst and hunger as well as fatigue.
  • Diabetes is diagnosed by blood sugar (glucose) testing.
  • The major complications of diabetes are both acute and chronic.

    • Acutely: dangerously elevated blood sugar, abnormally low blood sugar due to diabetes medications may occur.
    • Chronically: disease of the blood vessels (both small and large) which can damage the eye, kidneys, nerves, and heart may occur

  • Diabetes treatment depends...

Read the Diabetes (Type 1 and Type 2) article »




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