MedicineNet.com

trovafloxacin mesylate, Trovan

Causes of Fatigue Slideshow Sex-Drive Killers Slideshow Pictures Weight Gain Shockers Slideshow

GENERIC NAME: trovafloxacin mesylate

BRAND NAME: Trovan

DRUG CLASS AND MECHANISM: Many common infections in humans are caused by single cell organisms, called bacteria. Bacteria can grow and multiply, infecting different parts of the body. Medicines that control and eradicate these bacteria are called antibiotics. Trovafloxacin is an antibiotic that stops multiplication of bacteria by preventing the reproduction and repair of their genetic material (DNA). It is among a class of antibiotics called fluoroquinolones, a class that includes ciprofloxacin (Cipro), norfloxacin (Noroxin), ofloxacin (Floxin), levofloxacin (Levaquin), and lomefloxacin (Maxaquin). Trovafloxacin was approved by the FDA in 1997.

GENERIC AVAILABLE: No

PRESCRIPTION: Yes

PREPARATIONS: Tablets: 100mg (round; blue), 200mg (oval; blue)

STORAGE: Trovafloxacin should be stored below 86°F.

PRESCRIBED FOR: Trovafloxacin is used to treat infections of the sinuses, skin, lungs, and airways caused by susceptible bacteria. Trovafloxacin also is frequently used to treat infections of the urine and prostate, including those infections caused by bacteria that are resistant to other antibiotics. Trovafloxacin can also be used to treat various obstetric infections.

DOSING: Trovafloxacin usually is given once daily, with or without food. It is important to take it at least 2 hours before or 2 hours after antacids or mineral supplements containing iron, calcium, zinc, or magnesium which bind the antibiotic and prevent its absorption.

DRUG INTERACTIONS: Minerals with 2 or 3 positive charges, called divalent or trivalent ions, respectively, can bind onto trovafloxacin and other fluoroquinolones, markedly reducing the amount of drug that is absorbed. Such products, including antacids, should be taken at least 2 hours before or 2 hours after trovafloxacin. Other drugs which contain these ions and which can similarly interact with levofloxacin include sucralfate (Carafate) and didanosine, dDI

Other fluoroquinolones have been reported to increase blood levels of theophylline (Theo-Dur), warfarin (Coumadin), and cyclosporine (Sandimmune; Neoral). There have not yet been similar reports with trovafloxacin.

PREGNANCY: Trovafloxacin is not recommended for use in pregnant women since trovafloxacin causes joint and bone deformities in juvenile animals of several species.

NURSING MOTHERS: Trovafloxacin is not recommended for use in lactating women. Trovafloxacin causes joint and bone deformities in juvenile animals of several species. In fact, trovafloxacin is not recommended in persons under the age of 18 years.

SIDE EFFECTS: The most frequently reported side effects associated with trovafloxacin include abdominal pain, diarrhea, dizziness, headache, lightheadedness, nausea, vomiting, itching, and rash.

Trovafloxacinas well as other antibiotics in the fluoroquinolone class of antibiotics, has been associated with tendinitis and even rupture of tendons, particularly the Achilles tendon. Some physicians recommend that their patients discontinue vigorous exercise while they are taking fluoroquinolone antibiotics.

Reference: FDA Prescribing Information

Report Problems to the Food and Drug Administration   You are encouraged to report negative side effects of prescription drugs to the FDA. Visit the FDA MedWatch website or call 1-800-FDA-1088. Need help identifying pills and medications? Use the pill identifier tool on RxList.