trimipramine (Surmontil) (cont.)

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Sucking hard candy or chewing gum can help prevent dry mouth.

Trimipramine can increase a person's sensitivity to sunlight; patient's taking trimipramine should wear sunscreen and avoid sun exposure. Since trimipramine can impair the body's ability to sweat and adapt to hot environments, patients should avoid saunas and excessive heat. Trimipramine is used with caution in patients with seizures since it can increase the risk of seizures.

If trimipramine is discontinued abruptly headache, nausea, and general discomfort may occur. Therefore, it is recommended that the dose of antidepressant be reduced gradually when therapy is discontinued.

Antidepressants increased the risk of suicidal thinking and behavior in short-term studies in children and adolescents with depression and other psychiatric disorders. Anyone considering the use of trimipramine or any other antidepressant in a child or adolescent must balance this risk with the clinical need. Patients who are started on therapy should be closely observed for clinical worsening, suicidal thinking or behavior, and unusual changes in behavior.

Reference: FDA Prescribing Information


Last Editorial Review: 9/5/2012



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