trimethoprim, Trimpex (Discontinued Brand), Proloprim (Discontinued Brand), Primsol

  • Pharmacy Author:
    Omudhome Ogbru, PharmD

    Dr. Ogbru received his Doctorate in Pharmacy from the University of the Pacific School of Pharmacy in 1995. He completed a Pharmacy Practice Residency at the University of Arizona/University Medical Center in 1996. He was a Professor of Pharmacy Practice and a Regional Clerkship Coordinator for the University of the Pacific School of Pharmacy from 1996-99.

  • Medical and Pharmacy Editor: Jay W. Marks, MD
    Jay W. Marks, MD

    Jay W. Marks, MD

    Jay W. Marks, MD, is a board-certified internist and gastroenterologist. He graduated from Yale University School of Medicine and trained in internal medicine and gastroenterology at UCLA/Cedars-Sinai Medical Center in Los Angeles.

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GENERIC NAME: trimethoprim

BRAND NAMES: Primsol

DISCONTINUED BRANDS: Trimpex, Proloprim

PRESCRIPTION: Yes

GENERIC AVAILABLE: Yes

USES: Trimethoprim is used for the treatment of uncomplicated urinary tract infections due to susceptible bacteria.

SIDE EFFECTS: The most common side effects associated with trimethoprim are gastrointestinal, such as:

Taking trimethoprim with food may reduce some of these side effects. Trimethoprim may cause anemia due to a deficiency of folic acid. The anemia usually is mild and resolves when the trimethoprim is stopped. Patients who are folate-deficient, such as malnourished, alcoholic, geriatric, or pregnant patients, may be at greater risk for developing anemia with trimethoprim. Warning signs of anemia include white or bluish fingernails and unusual tiredness and weakness. Prolonged therapy can result in low platelet counts, low white blood cell counts, and other toxic effects on the blood cells.

Other important side effects are:

Rarely, the skin rash can progress to peeling or blistering. Some patients have photosensitivity reactions, that is, they develop skin rashes on parts of their body that are exposed to the sun.

Medically Reviewed by a Doctor on 3/29/2016

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