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GENERIC NAME: TRIMETHOBENZAMIDE - INJECTION (try-meth-oh-BENZ-uh-mide)

BRAND NAME(S): Tigan

Medication Uses | How To Use | Side Effects | Precautions | Drug Interactions | Overdose | Notes | Missed Dose | Storage

USES: This medication is used to treat nausea and vomiting.

HOW TO USE: This medication is used through intramuscular injection (IM).

SIDE EFFECTS: Diarrhea, headache, dizziness, drowsiness, dry mouth, or muscle cramps may occur as your body adjusts to the medication. If these effects persist or become bothersome, inform your doctor. Notify your doctor if you experience any of the following: unusual bleeding, depression, confusion, tremors, involuntary movements of the eyes/face/limbs, muscle spasms, rash, mouth sores, yellowing of the skin or eyes, blurred vision. If you notice other effects not listed above, contact your doctor or pharmacist.

PRECAUTIONS: Tell your doctor your medical history, especially: high fever, stomach problems (gastroenteritis), swelling/disease of the brain (encephalitis/encephalopathy), mineral (electrolyte) imbalance, any allergies. Do not give children trimethobenzamide to treat vomiting when the cause of vomiting is unknown. Trimethobenzamide may worsen Reye's Syndrome, a rare but serious illness. Do not give trimethobenzamide (or aspirin or acetaminophen) to a child with symptoms of Reye's Syndrome (sudden, severe, persistent vomiting; drowsiness or stupor; unusual behavior; and seizures). Call the doctor immediately if these symptoms are present. Children and teenagers should not use this drug if they have chickenpox, influenza, or any undiagnosed illness without first consulting a doctor about Reye's syndrome. If dizziness or drowsiness occurs, use caution engaging in activities requiring alertness such as driving. Limit alcohol because it adds to the dizziness/drowsiness effects of trimethobenzamide. This injectable form of trimethobenzamide is not recommended for use in children. This medication should be used only when clearly needed during pregnancy. Discuss the risks and benefits with your doctor. It is not known if this medication is excreted into breast milk. Consult your doctor before breast-feeding.




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trimethobenzamide-injection, Tigan

Introduction to nausea and vomiting

Nausea and vomiting are symptoms of an underlying disease and not a specific illness. Nausea is the sensation that the stomach wants to empty itself, while vomiting (emesis) or throwing up, is the act of forcible emptying of the stomach.

Vomiting is a violent act in which the stomach has to overcome the pressures that are normally in place to keep food and secretions within the stomach. The stomach almost turns itself inside out - forcing itself into the lower portion of the esophagus (the tube that connects the mouth to the stomach) during a vomiting episode.

What causes nausea or vomiting?

There are numerous causes of nausea and vomiting. These symptoms may be due to the following:

  • acute gastritis
  • central causes (signals from the brain)
  • association with other illnesses remote from the stomach
  • medications and medical treatments
  • ...

Read the Nausea and Vomiting article »




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