triamterene and hydrochlorothiazide, Maxzide, Dyazide (cont.)

Pharmacy Author:

Omudhome Ogbru, PharmD

Omudhome Ogbru, PharmD

Dr. Ogbru received his Doctorate in Pharmacy from the University of the Pacific School of Pharmacy in 1995. He completed a Pharmacy Practice Residency at the University of Arizona/University Medical Center in 1996. He was a Professor of Pharmacy Practice and a Regional Clerkship Coordinator for the University of the Pacific School of Pharmacy from 1996-99.

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Medical and Pharmacy Editor:

Jay W. Marks, MD

Jay W. Marks, MD

Jay W. Marks, MD, is a board-certified internist and gastroenterologist. He graduated from Yale University School of Medicine and trained in internal medicine and gastroenterology at UCLA/Cedars-Sinai Medical Center in Los Angeles.

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PREGNANCY: Triamterene/hydrochlorothiazide has not been adequately studied in pregnant women.

NURSING MOTHERS: Triamterene/hydrochlorothiazide has not been evaluated in nursing mothers. Hydrochlorothiazide is excreted in breast milk. There is some evidence that it may reduce production of breast milk.

SIDE EFFECTS: Side effects of triamterene/hydrochlorothiazide include abdominal pain, nausea, vomiting, rash, headache, dizziness, constipation, low blood pressure, electrolyte disturbance (for example, high potassium levels), muscle cramps, hypersensitivity, pancreatitis, and jaundice. Triamterene/hydrochlorothiazide may increase blood sugar (glucose) levels and precipitate or worsen diabetes. Patients allergic to sulfa drugs may also be allergic to hydrochlorothiazide because of the similarity in the chemical structure of the two drugs.

Reference: FDA Prescribing Information

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