triamterene and hydrochlorothiazide

Pharmacy Author:
Medical and Pharmacy Editor:

GENERIC NAME: triamterene and hydrochlorothiazide (HCTZ)

BRAND NAMES: Maxzide, Dyazide

DRUG CLASS AND MECHANISM: Triamterene/hydrochlorothiazide is an oral diuretic (water pill) that is used for treating high blood pressure (hypertension) and edema (water accumulation). It is a combination of two different diuretics. The FDA approved triamterene/hydrochlorothiazide in December 1965.

The kidneys control the amount of sodium and water within the body. Normally, blood circulates through the kidneys where much of the water, sodium and other small molecules are filtered out of the blood and into the tubules of the kidney. Once in the tubules, much of the water and sodium are reabsorbed back into the blood. The water and sodium that is not reabsorbed passes on through the tubules and becomes urine that is eliminated from the body. Diuretics affect the reabsorption of sodium and water from the tubules and thus, the amount of sodium and water retained or eliminated by the body. In addition to controlling sodium, the kidney also controls the amount of potassium that is retained or eliminated from the body.

Medically Reviewed by a Doctor on 10/29/2014

Report Problems to the Food and Drug Administration

You are encouraged to report negative side effects of prescription drugs to the FDA. Visit the FDA MedWatch website or call 1-800-FDA-1088.

Pill Finder Tool

Need help identifying pills and medications?
Use the pill identifier tool on RxList.

Back to Medications Index

Health Solutions From Our Sponsors