tretinoin, Retin A, Atralin, Renova, Avita, Altinac

Pharmacy Author:
Medical and Pharmacy Editor:

GENERIC NAME: tretinoin

BRAND NAME: Retin-A, Retin-A Micro, Atralin, Renova, Avita, Altinac

DRUG CLASS AND MECHANISM: Tretinoin is a derivative of vitamin A. It is used on the skin (topically) in the treatment of mild to moderate acne and on skin that has been damaged by excessive exposure to the sun. Tretinoin irritates the skin and causes the cells of the skin to grow (divide) and die more rapidly, increasing the turnover of cells. The number of layers of cells in the skin actually is reduced. In patients with acne, new cells replace the cells of existing pimples, and the rapid turnover of cells prevents new pimples from forming. By a similar mechanism, tretinoin can reduce some wrinkles, areas of darkened skin (hyperpigmentation), and rough areas of skin, all of which occur in sun-damaged skin. In patients with sun-damaged skin, improvements in the skin usually are seen within the first 3 to 4 weeks of treatment. Brown spots begin to fade after six to eight weeks. Wrinkles decrease or disappear after three to six months. Following application to the skin, a minimal amount of drug is absorbed into the body. The FDA approved topical tretinoin in 1971.

PRESCRIPTION: Yes

GENERIC AVAILABLE: Yes

PREPARATIONS: Gel: 0.01%, 0.025%, 0.04%, 0.05%, and 0.1%. Cream: 0.02%, 0.025%, 0.0375%, 0.05%, and 0.1%. Solution: 0.05%. Capsule: 10 mg.

STORAGE: Tretinoin should be store at room temperature, between 15-25 C (59 -77 F).




Report Problems to the Food and Drug Administration

You are encouraged to report negative side effects of prescription drugs to the FDA. Visit the FDA MedWatch website or call 1-800-FDA-1088.

Pill Finder Tool

Need help identifying pills and medications?
Use the pill identifier tool on RxList.


Back to Medications Index