trazodone, Desyrel (cont.)

Pharmacy Author:
Medical and Pharmacy Editor:
Medical and Pharmacy Editor:

Drugs that increase serotonin may cause bleeding. Therefore, combining trazodone with aspirin, nonsteroidal anti-inflammatory drugs, warfarin (Coumadin) or other drugs that affect bleeding may increase the likelihood of upper gastrointestinal bleeding.

PREGNANCY: There are no adequate studies of trazodone in pregnant women. Studies in animals have demonstrated effects on the developing fetus. Trazodone should only be used during pregnancy if the physician feels that its benefits outweigh its potential risks.

NURSING MOTHERS: Trazodone is secreted in breast milk. Therefore, caution should be used in prescribing trazodone to women who are breastfeeding.

SIDE EFFECTS: The most common side effects associated with trazodone are:

Priapism, (including clitoral priapism in women) a painful condition in which the penis (or clitoris) remains in an erect position for a prolonged period, has been reported in patients receiving trazodone. Priapism occasionally results in permanent impairment of erectile function or impotence. Patients should be warned of the possibility of priapism and told to discontinue the drug at once and consult with their physician if this reaction occurs. Trazodone also may affect ejaculation, orgasm and libido.

Medically Reviewed by a Doctor on 7/1/2014


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