tranexamic acid (Lysteda)
Omudhome Ogbru, PharmD
Omudhome Ogbru, PharmD
Dr. Ogbru received his Doctorate in Pharmacy from the University of the Pacific School of Pharmacy in 1995. He completed a Pharmacy Practice Residency at the University of Arizona/University Medical Center in 1996. He was a Professor of Pharmacy Practice and a Regional Clerkship Coordinator for the University of the Pacific School of Pharmacy from 1996-99.
Medical and Pharmacy Editor:
GENERIC NAME: tranexamic acid
BRAND NAME: Lysteda
DRUG CLASS AND MECHANISM: Tranexamic acid promotes the clotting of blood and thereby reduces bleeding due to heavy menstruation. Tranexamic acid is a man-made amino acid derivative that increases blood clotting by preventing the breakdown of fibrin. Fibrin is a protein and an important component of blood clots. It is broken down by another protein called plasmin. Tranexamic acid blocks the action of plasmin on fibrin and thereby prevents the breakdown of fibrin. This leads to stabilization and preservation of fibrin in blood clots, and this helps reduce bleeding during a heavy menstrual cycle. The FDA approved tranexamic acid in November 2009.
GENERIC AVAILABLE: Yes
PREPARATIONS: Tablets: 650 mg.
STORAGE: Tranexamic acid tablets should be stored between 15 C to 30 C (59 F to 86 F).
PRESCRIBED FOR: Tranexamic acid oral tablets are used for the treatment of heavy menstrual cycles.
DOSING: In females 12 years of age and older, the recommended dose is two 650 mg tablets (1300 mg) by mouth three times a day for a maximum of 5 days during the menstrual cycle. It may be administered without regard to meals. Tablets should be swallowed whole and not chewed or broken.
Safe and effective use of tranexamic acid is not determined in premenarcheal girls or girls under the age of 12.
Medically Reviewed by a Doctor on 5/16/2014
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