tranexamic acid (Lysteda)

  • Pharmacy Author:
    Omudhome Ogbru, PharmD

    Dr. Ogbru received his Doctorate in Pharmacy from the University of the Pacific School of Pharmacy in 1995. He completed a Pharmacy Practice Residency at the University of Arizona/University Medical Center in 1996. He was a Professor of Pharmacy Practice and a Regional Clerkship Coordinator for the University of the Pacific School of Pharmacy from 1996-99.

  • Medical and Pharmacy Editor: Jay W. Marks, MD
    Jay W. Marks, MD

    Jay W. Marks, MD

    Jay W. Marks, MD, is a board-certified internist and gastroenterologist. He graduated from Yale University School of Medicine and trained in internal medicine and gastroenterology at UCLA/Cedars-Sinai Medical Center in Los Angeles.

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GENERIC NAME: tranexamic acid




USES: Tranexamic acid oral tablets are used for the treatment of heavy menstrual cycles.

SIDE EFFECTS: Side effects of tranexamic acid are:

Tranexamic acid may increase the risk of forming blood clots.

PREPARATIONS: Tablets: 650 mg.


  • Concomitant use of tranexamic acid and birth control medications can increase the risk of blood clots.
  • Concomitant use with tissue plasminogen activators (used to prevent or treat blood clots) can reduce the effectiveness of tranexamic acid.
  • Concomitant use with Factor IX complex concentrates or anti-inhibitor coagulant concentrates that promote blood clots is not recommended due to the increased risk of blood clots.

PREGNANCY AND BREASTFEEDING SAFETY: Tranexamic acid is not approved for use in pregnant women. Moreover, there no adequate studies of tranexamic acid to determine safe and effective use in pregnant women. Tranexamic acid is present in breast milk in trace amounts; therefore, caution must be exercised before considering itsuse in nursing mothers.

STORAGE: Tranexamic acid tablets should be stored between 15 C to 30 C (59 F to 86 F).

DOSING: In females 12 years of age and older, the recommended dose is two 650 mg tablets (1300 mg) by mouth three times a day for a maximum of 5 days during the menstrual cycle. It may be administered without regard to meals. Tablets should be swallowed whole and not chewed or broken.

Medically Reviewed by a Doctor on 1/22/2016
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