tranexamic acid (injection, Cyklokapron)

  • Pharmacy Author:
    Omudhome Ogbru, PharmD

    Dr. Ogbru received his Doctorate in Pharmacy from the University of the Pacific School of Pharmacy in 1995. He completed a Pharmacy Practice Residency at the University of Arizona/University Medical Center in 1996. He was a Professor of Pharmacy Practice and a Regional Clerkship Coordinator for the University of the Pacific School of Pharmacy from 1996-99.

  • Medical and Pharmacy Editor: Jay W. Marks, MD
    Jay W. Marks, MD

    Jay W. Marks, MD

    Jay W. Marks, MD, is a board-certified internist and gastroenterologist. He graduated from Yale University School of Medicine and trained in internal medicine and gastroenterology at UCLA/Cedars-Sinai Medical Center in Los Angeles.

What is the dosage for tranexamic acid-injection?

  • Prior to tooth extraction, tranexamic acid should be administered at a dose of 10 mg per kg body weight of intravenously.
  • Thereafter, a dose of 10 mg per kg body weight should be given three to four times daily for 2 to 8 days after tooth extraction.

Which drugs or supplements interact with tranexamic acid-injection?

  • Concomitant use with tissue plasminogen activators (used to prevent or treat blood clots) can reduce the effectiveness of tranexamic acid.
  • Concomitant use with factor IX complex concentrates or anti-inhibitor coagulant concentrates that promote blood clots is not recommended due to the increased risk of blood clots.
Medically Reviewed by a Doctor on 4/15/2016
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