tranexamic acid (injection, Cyklokapron) (cont.)

Pharmacy Author:
Medical and Pharmacy Editor:

PREPARATIONS: Single dose injection (vials or ampules): 100 mg/ml

DRUG INTERACTIONS:

  • Concomitant use with tissue plasminogen activators (used to prevent or treat blood clots) can reduce the effectiveness of tranexamic acid.
  • Concomitant use with factor IX complex concentrates or anti-inhibitor coagulant concentrates that promote blood clots is not recommended due to the increased risk of blood clots.

PREGNANCY AND BREASTFEEDING SAFETY:

  • Tranexamic acid injection has not been adequately evaluated in pregnant women.
  • Tranexamic acid is present in breast milk in trace amounts; therefore, caution must be exercised when it is used in nursing mothers.

STORAGE: Tranexamic acid injection should be stored at room temperature, 15 C - 30 C (59 F - 86 F).

DOSING:

  • Prior to tooth extraction, tranexamic acid should be administered at a dose of 10 mg per kg body weight of intravenously.
  • Thereafter, a dose of 10 mg per kg body weight should be given three to four times daily for 2 to 8 days after tooth extraction.
Medically Reviewed by a Doctor on 4/15/2016


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