tranexamic acid (injection, Cyklokapron)

  • Pharmacy Author:
    Omudhome Ogbru, PharmD

    Dr. Ogbru received his Doctorate in Pharmacy from the University of the Pacific School of Pharmacy in 1995. He completed a Pharmacy Practice Residency at the University of Arizona/University Medical Center in 1996. He was a Professor of Pharmacy Practice and a Regional Clerkship Coordinator for the University of the Pacific School of Pharmacy from 1996-99.

  • Medical and Pharmacy Editor: Jay W. Marks, MD
    Jay W. Marks, MD

    Jay W. Marks, MD

    Jay W. Marks, MD, is a board-certified internist and gastroenterologist. He graduated from Yale University School of Medicine and trained in internal medicine and gastroenterology at UCLA/Cedars-Sinai Medical Center in Los Angeles.

19 Habits That Wreck Your Teeth

PREPARATIONS: Single dose injection (vials or ampules): 100 mg/ml

DRUG INTERACTIONS:

  • Concomitant use with tissue plasminogen activators (used to prevent or treat blood clots) can reduce the effectiveness of tranexamic acid.
  • Concomitant use with factor IX complex concentrates or anti-inhibitor coagulant concentrates that promote blood clots is not recommended due to the increased risk of blood clots.

PREGNANCY AND BREASTFEEDING SAFETY:

  • Tranexamic acid injection has not been adequately evaluated in pregnant women.
  • Tranexamic acid is present in breast milk in trace amounts; therefore, caution must be exercised when it is used in nursing mothers.

STORAGE: Tranexamic acid injection should be stored at room temperature, 15 C - 30 C (59 F - 86 F).

DOSING:

  • Prior to tooth extraction, tranexamic acid should be administered at a dose of 10 mg per kg body weight of intravenously.
  • Thereafter, a dose of 10 mg per kg body weight should be given three to four times daily for 2 to 8 days after tooth extraction.
Medically Reviewed by a Doctor on 4/15/2016
FDA Logo

Report Problems to the Food and Drug Administration

You are encouraged to report negative side effects of prescription drugs to the FDA. Visit the FDA MedWatch website or call 1-800-FDA-1088.

RxList Logo

Need help identifying pills and medications?

Use the pill identifier tool on RxList.

Subscribe to MedicineNet's Newsletters

Get the latest health and medical information delivered direct to your inbox!

By clicking Submit, I agree to the MedicineNet's Terms & Conditions & Privacy Policy and understand that I may opt out of MedicineNet's subscriptions at any time.

Health Solutions From Our Sponsors