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- What is tranexamic acid-injection, and how does it work (mechanism of action)?
- What brand names are available for tranexamic acid-injection?
- Is tranexamic acid-injection available as a generic drug?
- Do I need a prescription for tranexamic acid-injection?
- What are the uses for tranexamic acid-injection?
- What are the side effects of tranexamic acid-injection?
- What is the dosage for tranexamic acid-injection?
- Which drugs or supplements interact with tranexamic acid-injection?
- Is tranexamic acid-injection safe to take if I'm pregnant or breastfeeding?
- What else should I know about tranexamic acid-injection?
What is tranexamic acid-injection, and how does it work (mechanism of action)?
- Tranexamic acid promotes the clotting of blood and thereby reduces bleeding due to tooth extractions in people with hemophilia. People with hemophilia bleed easily because they lack a specific blood protein necessary for forming blood clots.
- Tranexamic acid is a man-made amino acid derivative that increases blood clotting by preventing the breakdown of fibrin. Fibrin is a protein and an important component of blood clots. It is broken down by another protein called plasmin. Tranexamic acid blocks the action of plasmin on fibrin and thereby prevents the breakdown of fibrin. This leads to stabilization and preservation of fibrin in blood clots. This helps reduce bleeding after a tooth extraction.
- The FDA approved tranexamic acid injection in December, 1986.
What brand names are available for tranexamic acid-injection?
Is tranexamic acid-injection available as a generic drug?
GENERIC AVAILABLE: Yes
Do I need a prescription for tranexamic acid-injection?
What are the uses for tranexamic acid-injection?
Tranexamic acid injection is used short-term (two to eight days) to prevent bleeding following tooth extraction in people with hemophilia.
What are the side effects of tranexamic acid-injection?
Common side effects of tranexamic acid injection include:
Other less common side effects side effects include:
- Allergic dermatitis
- Low blood pressure (hypotension)
- Possible serious side effects include:
- Deep vein thrombosis (blood clot in the leg)
- Pulmonary embolism (blood clot in the lung)
- Cerebral thrombosis
- Acute renal cortical necrosis
- Central retinal artery and vein obstruction
- Visual impairment
Report Problems to the Food and Drug Administration
You are encouraged to report negative side effects of prescription drugs to the FDA. Visit the FDA MedWatch website or call 1-800-FDA-1088.
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