tranexamic acid (injection, Cyklokapron)

  • Pharmacy Author:
    Omudhome Ogbru, PharmD

    Dr. Ogbru received his Doctorate in Pharmacy from the University of the Pacific School of Pharmacy in 1995. He completed a Pharmacy Practice Residency at the University of Arizona/University Medical Center in 1996. He was a Professor of Pharmacy Practice and a Regional Clerkship Coordinator for the University of the Pacific School of Pharmacy from 1996-99.

  • Medical and Pharmacy Editor: Jay W. Marks, MD
    Jay W. Marks, MD

    Jay W. Marks, MD

    Jay W. Marks, MD, is a board-certified internist and gastroenterologist. He graduated from Yale University School of Medicine and trained in internal medicine and gastroenterology at UCLA/Cedars-Sinai Medical Center in Los Angeles.

What is tranexamic acid-injection, and how does it work (mechanism of action)?

  • Tranexamic acid promotes the clotting of blood and thereby reduces bleeding due to tooth extractions in people with hemophilia. People with hemophilia bleed easily because they lack a specific blood protein necessary for forming blood clots.
  • Tranexamic acid is a man-made amino acid derivative that increases blood clotting by preventing the breakdown of fibrin. Fibrin is a protein and an important component of blood clots. It is broken down by another protein called plasmin. Tranexamic acid blocks the action of plasmin on fibrin and thereby prevents the breakdown of fibrin. This leads to stabilization and preservation of fibrin in blood clots. This helps reduce bleeding after a tooth extraction.
  • The FDA approved tranexamic acid injection in December, 1986.

What brand names are available for tranexamic acid-injection?


Is tranexamic acid-injection available as a generic drug?


Do I need a prescription for tranexamic acid-injection?


What are the uses for tranexamic acid-injection?

Tranexamic acid injection is used short-term (two to eight days) to prevent bleeding following tooth extraction in people with hemophilia.

What are the side effects of tranexamic acid-injection?

Common side effects of tranexamic acid injection include:

Other less common side effects side effects include:

Medically Reviewed by a Doctor on 4/15/2016
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