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February 9, 2012

Toxic Shock Syndrome (TSS)

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What causes toxic shock syndrome?

Toxic shock syndrome (TSS) is a life-threatening condition caused by toxins produced by certain types of infecting bacteria. The condition has been most often associated with the use of tampons in menstruating women. In 1980, an outbreak of TSS was linked to the use of one brand of superabsorbent tampons. Although this outbreak was linked to toxins produced by the Staphylococcus aureus bacteria, TSS can also be caused by toxins from the group A Streptococcus bacteria. The condition is sometimes subdivided and referred to as staphylococcal TSS and streptococcal TSS.

Although this disease has been frequently linked to the use of tampons in menstruating women, it can affect people of any gender and any age. About half of the reported cases have been linked to the use of tampons in menstruating women, while the remaining cases are due to other situations. Tampons, especially when left in place for a long period of time, are thought to provide a breeding ground for the bacteria that subsequently release toxins to cause TSS. When not linked to tampon use, TSS can occur as a complication of surgery or skin infections.

What are the risk factors for toxic shock syndrome?

In the U.S., the incidence is approximately 1/100,000 women 15-44 years of age, with the overall incidence estimated at about twice that number.

Risk factors are the use of tampons (especially when left in place for an extended time period) and barrier contraceptive devices in women, surgery (especially nasal surgery), the use of wound packings (such as nasal packings), and postoperative wound infection.




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Toxic Shock Syndrome

What is Staphylococcus?

Staphylococcus is a group of bacteria that can cause a number of diseases as a result of infection of various tissues of the body. Staphylococcus is more familiarly known as Staph (pronounced "staff"). Staph-related illness can range from mild and requiring no treatment to severe and potentially fatal.

The name Staphylococcus comes from the Greek staphyle, meaning a bunch of grapes, and kokkos, meaning berry, and that is what Staph bacteria look like under the microscope, like a bunch of grapes or little round berries. (In technical terms, these are gram-positive, facultative anaerobic, usually unencapsulated cocci.)

Over 30 different types of Staphylococci can infect humans, but most infections are caused by Staphylococcus aureus. Staphylococci can be found normally in the nose and on the skin (and less commonly in other locations) of 25%-30% of healthy adults. In the majo...

Read the Staph Infection (Staphylococcus Aureus) article »







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