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November 25, 2009
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Toxic Shock Syndrome (TSS)

Medical Author: Jerry Balentine, DO, FACEP
Medical Editor: Melissa Conrad Stöppler, MD, and William C. Shiel Jr., MD, FACP, FACR

What causes toxic shock syndrome?

Toxic shock syndrome (TSS) is a life-threatening condition caused by toxins produced by certain types of infecting bacteria. The condition has been most often associated with the use of tampons in menstruating women. In 1980, an outbreak of TSS was linked to the use of one brand of superabsorbent tampons. Although this outbreak was linked to toxins produced by the Staphylococcus aureus bacteria, TSS can also be caused by toxins from the group A Streptococcus bacteria. The condition is sometimes subdivided and referred to as staphylococcal TSS and streptococcal TSS.

Although this disease has been frequently linked to the use of tampons in menstruating women, it can affect people of any gender and any age. About half of the reported cases have been linked to the use of tampons in menstruating women, while the remaining cases are due to other situations. Tampons, especially when left in place for a long period of time, are thought to provide a breeding ground for the bacteria that subsequently release toxins to cause TSS. When not linked to tampon use, TSS can occur as a complication of surgery or skin infections.

What are the risk factors for toxic shock syndrome?

In the U.S., the incidence is approximately 1/100,000 women 15-44 years of age, with the overall incidence estimated at about twice that number.

Risk factors are the use of tampons (especially when left in place for an extended time period) and barrier contraceptive devices in women, surgery (especially nasal surgery), the use of wound packings (such as nasal packings), and postoperative wound infection.



Next: What are the signs and symptoms of toxic shock syndrome? »

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Toxic Shock Syndrome

Introduction to nausea and vomiting

Nausea and vomiting are symptoms of an underlying disease and not a specific illness. Nausea is the sensation that the stomach wants to empty itself, while vomiting (emesis) or throwing up, is the act of forcible emptying of the stomach.

Vomiting is a violent act in which the stomach has to overcome the pressures that are normally in place to keep food and secretions within the stomach. The stomach almost turns itself inside out - forcing itself into the lower portion of the esophagus (the tube that connects the mouth to the stomach) during a vomiting episode.

What causes nausea or vomiting?

There are numerous causes of nausea and vomiting. These symptoms may be due to the following:

  • acute gastritis
  • central causes (signals from the brain)
  • association with other illnesses remote from the stomach
  • medications and medical treatments
  • ...

Read the Nausea and Vomiting article »










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