- What is torsemide, and how does it work?
- What brand names are available for torsemide?
- Is it available as a generic drug?
- Do I need a prescription for it?
- What are the uses for torsemide?
- Torsemide side effects
- What dosages are available for torsemide, and how do I take it?
- Which drugs or supplements cause interactions?
- Is it safe to take this drug if I'm pregnant or breastfeeding?
- Storage and FDA approval
- Overdose information
What is torsemide, and how does it work?
Torsemide (Demadex) is a potent drug that's a diuretic (water pill). This medicine causes a profound increase in urine output (diuresis) by preventing the kidney from retaining water. Specifically, it blocks the reabsorption back into the blood of sodium and water that has been filtered out of the blood in the kidneys.
It is in a class of diuretic drugs called "loop" diuretics, which also includes the drugs furosemide (Lasix) and bumetanide (Bumex). Torsemide 10-20 mg is approximately equivalent to 1 mg of bumetanide and 40 mg of furosemide. The potent diuretic effect of torsemide can cause the loss of large amounts of body water leading to dehydration as well as the loss of electrolytes (for example, sodium, potassium, magnesium, and calcium). Therefore, careful medical supervision is necessary during treatment.
What brand names are available for torsemide?
Demadex is the brand name for this medication in the US.
Is it available as a generic drug?
Yes, it's available as a generic drug.
Do I need a prescription for it?
Yes, your medical doctor or health care professional will need to write you a prescription for the medication.
What are the uses for torsemide?
This drug is prescribed by doctors to treat several diseases and conditions.
- Torsemide (Demadex) is used for the medical treatment of edema (water retention) due to congestive heart failure, kidney disease, chronic kidney failure, or liver disease.
- It also is used alone or combined with other antihypertensive medications for the treatment of high blood pressure (hypertension).
Who shouldn't take Demadex?
- Patient's shouldn't take Demadex if they are allergic to it or to sulfonylureas to which it is related.
- Don't take it if you aren't able to urinate.
- Patients with liver disease with cirrhosis and ascites should use this drug with caution because sudden changes in fluid and electrolyte balance can cause hepatic coma.
Torsemide side effects
- Dry mouth
- Reduced kidney function
- Heart arrhythmias
- Muscle aches and pains
Possible side effects of this medication reported often include:
- Excessive urination
- Runny nose
- ECG abnormality
- Joint pain
- Stomach upset
- Sore throat
- Muscle pain
Possible serious side effects adverse effects include:
- Atrial fibrillation
- Chest pain
- Gastrointestinal bleeding
- High blood sugar (hyperglycemia)
- Increased uric acid (hyperuricemia)
- Low blood potassium (hypokalemia)
- Low blood pressure (hypotension)
- Dehydration (symptoms listed previously)
- Shunt thrombosis
- Rectal bleeding
- Ventricular tachycardia
- Serious skin reactions (Stevens-Johnson syndrome, toxic epidermal necrolysis)
- Allergic reactions
- Reduced number of white blood cells and platelets
Demadex can cause dehydration and loss of potassium and other electrolytes. Low potassium levels (hypokalemia) can cause abnormal heart beats especially in people with heart disease or those taking the medicine digoxin (Lanoxin). Levels of potassium and other electrolytes should be monitored during medical treatment with this medicine.
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