topiramate, Topamax, Qudexy XR, Topamax Sprinkle, Topiragen, Trokendi XR

  • Pharmacy Author:
    Omudhome Ogbru, PharmD

    Dr. Ogbru received his Doctorate in Pharmacy from the University of the Pacific School of Pharmacy in 1995. He completed a Pharmacy Practice Residency at the University of Arizona/University Medical Center in 1996. He was a Professor of Pharmacy Practice and a Regional Clerkship Coordinator for the University of the Pacific School of Pharmacy from 1996-99.

  • Medical and Pharmacy Editor: Jay W. Marks, MD
    Jay W. Marks, MD

    Jay W. Marks, MD

    Jay W. Marks, MD, is a board-certified internist and gastroenterologist. He graduated from Yale University School of Medicine and trained in internal medicine and gastroenterology at UCLA/Cedars-Sinai Medical Center in Los Angeles.

A Guide to Migraine Headaches

SIDE EFFECTS: The most common side effects of topiramate are:

Other important side effects include:

  • increased ammonia levels,
  • metabolic acidosis,
  • kidney stones,
  • decreased sweating, and
  • increased body temperature.

WARNING: Topiramate may cause sudden onset of vision and eye problems. Symptoms typically occur within the first month of therapy, with patients reporting an acute onset of decreased vision and/or eye pain. Eye examination revealed myopia (nearsightedness), redness, decreased depth of the anterior chamber of the eye and elevated ocular pressure, with or without dilation of the pupils. Fluid accumulation within the eye may displace the lens and iris anteriorly causing secondary angle closure glaucoma. If patients develop this syndrome, the treatment is to discontinue topiramate as rapidly as possible, according to the judgment of the treating physician.

Antiepileptic medications have been associated with increased risk of suicidal thinking and behavior. Anyone considering the use of antiepileptic drugs must balance this risk of suicide with the clinical need. Patients who are started on therapy should be closely observed for clinical worsening, suicidal thoughts, or unusual changes in behavior.

PRESCRIPTION: Yes

GENERIC AVAILABLE: Yes

PREPARATIONS:

  • Tablets: 25, 50, 100, 200 mg
  • Sprinkle capsules: 15 and 25 mg
  • Capsule (Extended Release): 25, 50, 100, 150, 200 mg

STORAGE:

  • Topiramate tablets should be stored at room temperature, 15 C to 30 C (59F to 86 F).
  • Sprinkle capsules should be stored at or below 25 C (77 F).
Medically Reviewed by a Doctor on 8/4/2015

Quick GuideMigraine or Headache? Migraine Symptoms, Triggers, Treatment

Migraine or Headache? Migraine Symptoms, Triggers, Treatment
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