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- What is tolmetin, and how does it work (mechanism of action)?
- Is tolmetin available as a generic drug?
- Do I need a prescription for tolmetin?
- What are the side effects of tolmetin?
- What is the dosage for tolmetin?
- Which drugs or supplements interact with tolmetin?
- Is tolmetin safe to take if I'm pregnant or breastfeeding?
- What else should I know about tolmetin?
What is tolmetin, and how does it work (mechanism of action)?
Tolmetin is a nonsteroidal anti-inflammatory drug (NSAID) that is effective in treating fever, pain, and inflammation in the body. It is similar to ibuprofen (Motrin or Advil), naproxen (Naprosyn), and others. As a group, NSAIDs are non-narcotic relievers of mild to moderate pain of many causes, including injury, menstrual cramps, arthritis, and other musculoskeletal conditions. They work by reducing the levels of prostaglandins, chemicals that are responsible for pain, fever, and inflammation. Tolmetin blocks the enzyme that makes prostaglandins (cyclooxygenase), resulting in lower concentrations of prostaglandins. As a consequence, inflammation, pain and fever are reduced. The FDA approved Tolectin in March 1976.
Is tolmetin available as a generic drug?
GENERIC AVAILABLE: Yes
Do I need a prescription for tolmetin?
What are the side effects of tolmetin?
Most patients benefit from tolmetin and other NSAIDs with few side effects. However, serious side effects can occur, and generally tend to be dose related. Therefore, it is advisable to use the lowest effective dose to minimize side effects. The most common side effects of tolmetin involve the gastrointestinal system, and these include:
- abdominal pain,
- serious gastrointestinal bleeding,
- liver toxicity,
- stomach ulceration
- black tarry stools, and
Tolmetin should be avoided by patients with a history of asthma, hives, or other allergic reactions to aspirin or other NSAIDs. Rare but severe allergic reactions have been reported in such individuals. It also should be avoided by patients with peptic ulcer disease or poor kidney function, since this medication can aggravate both conditions.
Other important side effects include:
- heart attacks
- accumulation of fluid, and
- increased chance ofheart failure.
Quick GuideOsteoarthritis (OA): Treatment, Symptoms, Diagnosis
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