GENERIC NAME: tolazamide

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BRAND NAME: Tolinase

DRUG CLASS AND MECHANISM: Tolazamide is an oral medication used to treat high blood glucose in patients with type 2 diabetes mellitus. It is a first generation sulfonylurea used in combination with exercise and dietary modifications to lower blood glucose in patients. Tolazamide stimulates the release of insulin from the pancreatic beta cells. Insulin is responsible for regulating how the body uses and stores glucose. It also reduces the production of glucose from the liver and increases the sensitivity of cells throughout the body to insulin. By increasing muslin sensitivity, the cells remove more glucose from the blood. Tolazamide was approved by the FDA in 1965.

PRESCRIBED FOR: Tolazamide is used with diet and exercise to reduce blood glucose in patients with type 2 diabetes mellitus.

Medically Reviewed by a Doctor on 8/17/2015

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