tolazamide (Tolinase)

  • Pharmacy Author:
    Omudhome Ogbru, PharmD

    Dr. Ogbru received his Doctorate in Pharmacy from the University of the Pacific School of Pharmacy in 1995. He completed a Pharmacy Practice Residency at the University of Arizona/University Medical Center in 1996. He was a Professor of Pharmacy Practice and a Regional Clerkship Coordinator for the University of the Pacific School of Pharmacy from 1996-99.

  • Medical and Pharmacy Editor: Jay W. Marks, MD
    Jay W. Marks, MD

    Jay W. Marks, MD

    Jay W. Marks, MD, is a board-certified internist and gastroenterologist. He graduated from Yale University School of Medicine and trained in internal medicine and gastroenterology at UCLA/Cedars-Sinai Medical Center in Los Angeles.

Type 2 Diabetes Warning Signs

BRAND NAME: Tolinase

DRUG CLASS AND MECHANISM: Tolazamide is an oral medication used to treat high blood glucose in patients with type 2 diabetes mellitus. It is a first generation sulfonylurea used in combination with exercise and dietary modifications to lower blood glucose in patients. Tolazamide stimulates the release of insulin from the pancreatic beta cells. Insulin is responsible for regulating how the body uses and stores glucose. It also reduces the production of glucose from the liver and increases the sensitivity of cells throughout the body to insulin. By increasing muslin sensitivity, the cells remove more glucose from the blood. Tolazamide was approved by the FDA in 1965.

PRESCRIBED FOR: Tolazamide is used with diet and exercise to reduce blood glucose in patients with type 2 diabetes mellitus.

SIDE EFFECTS:

Side effects associated with tolazamide therapy include

Medically Reviewed by a Doctor on 8/17/2015

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