tobramycin and dexamethasone, Tobradex, Tobradex ST

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GENERIC NAME: tobramycin and dexamethasone

BRAND NAME: Tobradex, Tobradex ST

DRUG CLASS AND MECHANISM: Tobradex is a combination of the antibiotic, tobramycin, plus the anti-inflammatory corticosteroid, dexamethasone (Decadron, DePaxe). The combination is used to treat conjunctivitis (inflammation of the inner side of the eyelids or pinkeye) when bacterial infection is thought to be the cause of the inflammation. Dexamethasone is a synthetic (man-made) corticosteroid. Corticosteroids are naturally-occurring chemicals produced by the adrenal glands. Corticosteroids affect the function of many cells within the body and suppress the immune system. Corticosteroids also block inflammation and are used in a wide variety of inflammatory diseases affecting many organs. Tobramycin is an antibiotic that is active against Staphylococci (S. aureus and S. epidermidis), Streptococcus pneumoniae, Pseudomonas aeruginosa, Escherichia coli, Klebsiellla pneumoniae and many other types of bacteria. Tobradex was approved by the FDA in 1988.

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