tobramycin ophthalmic solution (Tobrex) (cont.)

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Medical and Pharmacy Editor:

PRESCRIBED FOR: Tobramycin ophthalmic solution is prescribed for the treatment of bacterial infections of the eye.

DOSING: The initial dose for adults and children two months old or greater is 1 to 2 drops every 2 to 4 hours in the infected eye. For severe infections, up to 2 drops every hour may be used until improvement is seen, at which time the dose should be reduced.

DRUG INTERACTIONS: There are no known drug interactions with tobramycin ophthalmic solution.

PREGNANCY: There is no evidence of harm to the fetus in animal studies with systemic tobramycin use; no direct studies in humans have been conducted. Blood levels are undetectable after ophthalmic tobramycin use.

NURSING MOTHERS: Tobramycin ophthalmic solution is not absorbed into the body at detectable levels, and therefore not expected to be present in the breast milk. However, breast feeding is not recommended due to the potential for adverse effects in the infant.

SIDE EFFECTS: Side effects are rare. Less than 1% report sensitivity reactions including swelling and itching of the eyelid, and reddening of the eye (conjunctiva).

REFERENCE: FDA Prescribing Information

Medically Reviewed by a Doctor on 5/16/2014

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