tobramycin ophthalmic solution (Tobrex)
Omudhome Ogbru, PharmD
Omudhome Ogbru, PharmD
Dr. Ogbru received his Doctorate in Pharmacy from the University of the Pacific School of Pharmacy in 1995. He completed a Pharmacy Practice Residency at the University of Arizona/University Medical Center in 1996. He was a Professor of Pharmacy Practice and a Regional Clerkship Coordinator for the University of the Pacific School of Pharmacy from 1996-99.
Medical and Pharmacy Editor:
GENERIC NAME: tobramycin ophthalmic solution
BRAND NAMES: Tobrex
DRUG CLASS AND MECHANISM: Tobramycin is an aminoglycoside antibiotic that interferes with bacterial production of proteins, ultimately leading to bacterial death. Tobramycin, like other aminoglycoside antibiotics, targets various gram-positive and gram-negative bacteria. Targeted organisms include Staphylococcus aureus, Staphylococcus epidermidis, Streptococci, Pseudomonas aeruginosa, Escherichia coli, Klebsiella pneumoniae, Enterobacter aerogenes, Proteus mirabilis, Morganella morganii, Proteus vulgaris (most strains), Haemophilus influenzae, Haemophilus aegyptius, Moraxella lacunata, Acinetobacter calcoaceticus, and some Neisseria species. The FDA approved tobramycin ophthalmic solution in December 1980.
GENERIC AVAILABLE: Yes
PREPARATIONS: Ophthalmic Solution 0.3%
STORAGE: Tobramycin ophthalmic solution should be stored at room temperature, between 15 C to 30 C (59 F to 86 F). Some preparations may be refrigerated and stored between 2 C to 8 C (36 F to 46 F).
PRESCRIBED FOR: Tobramycin ophthalmic solution is prescribed for the treatment of bacterial infections of the eye.
DOSING: The initial dose for adults and children two months old or greater is 1 to 2 drops every 2 to 4 hours in the infected eye. For severe infections, up to 2 drops every hour may be used until improvement is seen, at which time the dose should be reduced.
DRUG INTERACTIONS: There are no known drug interactions with tobramycin ophthalmic solution.
Medically Reviewed by a Doctor on 5/16/2014
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