tobramycin optic (Tobrex) (cont.)

Pharmacy Author:
Medical and Pharmacy Editor:

Administration of eye drops may cause temporary vision problems including blurred vision. Patients should not engage in dangerous activities such as driving until their vision improves.

Although serious allergic reactions to tobramycin are unlikely, patient suspected of experiencing such a reaction must seek emergency medical help. Symptoms of a serious allergic reaction may include:

  • difficulty breathing,
  • swelling of the tongue,
  • face, or throat, and
  • severe rash.



PREPARATIONS: 0.3% ophthalmic solution (eye drops or ointment)

STORAGE: Tobramycin ophthalmic solution should be stored at room temperature between 20 C and 25 (68 F and 77 F).

PRESCRIBED FOR: Tobramycin ophthalmic solution is used to treat external eye infections caused by susceptible bacteria.

DOSING: For all patients ≥ 2 months of age: Instill 1-2 drops into the infected eye every 4 to 6 hours. For severe infections, instill 2 drops into the infected eye every 30 minutes to an hour until improvement and then reduce to less frequent dosing intervals as indicated. Patients using tobramycin ophthalmic solution:

  • should wash their hands thoroughly with soap and water before and after using eye drops;
  • should be advised not to wear contact lenses during treatment of active eye infections;
  • must take care to avoid touching the dropper tip to the eye while administrating eye drops;
  • should wait for at least 5 minutes between applications if other eye drop preparations also are used.

DRUG INTERACTIONS: Information on possible drug interactions with tobramycin ophthalmic drops is not found. However, as use of therapeutic levels of tobramycin eye drops does not result into clinically meaningful levels of drug in the blood, the potential for drug interaction with other agents is relatively low. Patients using other eye drops or those with pre-existing conditions of the eye should check with their doctor or pharmacists before using tobramycin ophthalmic drops.

Medically Reviewed by a Doctor on 6/9/2015

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