tobramycin optic (Tobrex)

  • Pharmacy Author:
    Omudhome Ogbru, PharmD

    Dr. Ogbru received his Doctorate in Pharmacy from the University of the Pacific School of Pharmacy in 1995. He completed a Pharmacy Practice Residency at the University of Arizona/University Medical Center in 1996. He was a Professor of Pharmacy Practice and a Regional Clerkship Coordinator for the University of the Pacific School of Pharmacy from 1996-99.

  • Medical and Pharmacy Editor: Charles Patrick Davis, MD, PhD
    Charles Patrick Davis, MD, PhD

    Charles Patrick Davis, MD, PhD

    Dr. Charles "Pat" Davis, MD, PhD, is a board certified Emergency Medicine doctor who currently practices as a consultant and staff member for hospitals. He has a PhD in Microbiology (UT at Austin), and the MD (Univ. Texas Medical Branch, Galveston). He is a Clinical Professor (retired) in the Division of Emergency Medicine, UT Health Science Center at San Antonio, and has been the Chief of Emergency Medicine at UT Medical Branch and at UTHSCSA with over 250 publications.

What is tobramcyin-ophthalmic drops, and how does it work (mechanism of action)?

Tobramycin (Tobrex) is an antibiotic eye drop. Tobramycin is an aminoglycoside antibiotic that kills susceptible bacteria by blocking bacterial protein synthesis. Death of susceptible bacteria occurs because of the lack of functional proteins. Tobramycin treats only bacterial eye infections and does not work for other types of eye infections.

The FDA approved tobramycin eye drops in December 1980. In addition to eye drops, tobramycin is also available as 0.3% ointment which is also used to treat external bacterial infections of the eye.

What brand names are available for tobramcyin-ophthalmic drops?

Tobrex

Is tobramcyin-ophthalmic drops available as a generic drug?

GENERIC AVAILABLE: Yes

Do I need a prescription for tobramcyin-ophthalmic drops?

Yes

What are the side effects of tobramcyin-ophthalmic drops?

Side effects associated with the use of tobramycin eye drops are mostly limited to the area(s) of application. Reported side effects include:

  • tearing,
  • swelling of the eye, and
  • itching, stinging, or burning of the eye.

Administration of eye drops may cause temporary vision problems including blurred vision. Patients should not engage in dangerous activities such as driving until their vision improves.

Although serious allergic reactions to tobramycin are unlikely, patient suspected of experiencing such a reaction must seek emergency medical help. Symptoms of a serious allergic reaction may include:

  • difficulty breathing,
  • swelling of the tongue,
  • face, or throat, and
  • severe rash.

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