tobramycin optic (Tobrex)

  • Pharmacy Author:
    Omudhome Ogbru, PharmD

    Dr. Ogbru received his Doctorate in Pharmacy from the University of the Pacific School of Pharmacy in 1995. He completed a Pharmacy Practice Residency at the University of Arizona/University Medical Center in 1996. He was a Professor of Pharmacy Practice and a Regional Clerkship Coordinator for the University of the Pacific School of Pharmacy from 1996-99.

  • Medical and Pharmacy Editor: Charles Patrick Davis, MD, PhD
    Charles Patrick Davis, MD, PhD

    Charles Patrick Davis, MD, PhD

    Dr. Charles "Pat" Davis, MD, PhD, is a board certified Emergency Medicine doctor who currently practices as a consultant and staff member for hospitals. He has a PhD in Microbiology (UT at Austin), and the MD (Univ. Texas Medical Branch, Galveston). He is a Clinical Professor (retired) in the Division of Emergency Medicine, UT Health Science Center at San Antonio, and has been the Chief of Emergency Medicine at UT Medical Branch and at UTHSCSA with over 250 publications.

View the Eye Diseases and Conditions Slideshow Pictures

GENERIC NAME: tobramycin ophthalmic solution

BRAND NAME: Tobrex

DRUG CLASS AND MECHANISM: Tobramycin (Tobrex) is an antibiotic eye drop. Tobramycin is an aminoglycoside antibiotic that kills susceptible bacteria by blocking bacterial protein synthesis. Death of susceptible bacteria occurs because of the lack of functional proteins. Tobramycin treats only bacterial eye infections and does not work for other types of eye infections.

The FDA approved tobramycin eye drops in December 1980. In addition to eye drops, tobramycin is also available as 0.3% ointment which is also used to treat external bacterial infections of the eye.

PRESCRIBED FOR: Tobramycin ophthalmic solution is used to treat external eye infections caused by susceptible bacteria.

SIDE EFFECTS: Side effects associated with the use of tobramycin eye drops are mostly limited to the area(s) of application. Reported side effects include:

  • tearing,
  • swelling of the eye, and
  • itching, stinging, or burning of the eye.

Administration of eye drops may cause temporary vision problems including blurred vision. Patients should not engage in dangerous activities such as driving until their vision improves.

Although serious allergic reactions to tobramycin are unlikely, patient suspected of experiencing such a reaction must seek emergency medical help. Symptoms of a serious allergic reaction may include:

  • difficulty breathing,
  • swelling of the tongue,
  • face, or throat, and
  • severe rash.

PRESCRIPTION: Yes

GENERIC AVAILABLE: Yes

PREPARATIONS: 0.3% ophthalmic solution (eye drops or ointment)

Medically Reviewed by a Doctor on 6/9/2015
Eye Conditions Quiz: Test Your IQ
FDA Logo

Report Problems to the Food and Drug Administration

You are encouraged to report negative side effects of prescription drugs to the FDA. Visit the FDA MedWatch website or call 1-800-FDA-1088.

RxList Logo

Need help identifying pills and medications?

Use the pill identifier tool on RxList.

Subscribe to MedicineNet's Newsletters

Get the latest health and medical information delivered direct to your inbox!

By clicking Submit, I agree to the MedicineNet's Terms & Conditions & Privacy Policy and understand that I may opt out of MedicineNet's subscriptions at any time.

Health Solutions From Our Sponsors