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- What is tizanidine-oral, and how does it work (mechanism of action)?
- What brand names are available for tizanidine-oral?
- Is tizanidine-oral available as a generic drug?
- Do I need a prescription for tizanidine-oral?
- What are the uses for tizanidine-oral?
- What are the side effects of tizanidine-oral?
- What is the dosage for tizanidine-oral?
- Which drugs or supplements interact with tizanidine-oral?
- Is tizanidine-oral safe to take if I'm pregnant or breastfeeding?
- What else should I know about tizanidine-oral?
What is the dosage for tizanidine-oral?
Initially take 2 - 4 mg by mouth every 6 to 8 hours for up to 3 doses in 24 hours. Increase by 2 to 4 mg until satisfactory response is achieved; however, the maximum dose is 36 mg per day.
Which drugs or supplements interact with tizanidine-oral?
Tizanidine should not be used with:
- ciprofloxacin (Cipro),
- amiodarone (Cordarone),
- cimetidine (Tagamet),
- oral contraceptives,
- acyclovir (Zovirax), and
- fluvoxamine (Luvox).
These medications can slow down the breakdown of tizanidine and lead to increased sedation, drowsiness and slowed reflexes.
Tizanidine should be used with caution with medications like:
- alprazolam (Xanax),
- clonazepam (Klonopin),
- diazepam (Valium),
- zolpidem (Ambien),
- oxycodone (Roxicodone),
- hydromorphone (Dilaudid),
- amitriptyline (Elavil),
- nortriptyline (Pamelor) and
These medications can further increase the side effects of tizanidine.
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