PREGNANCY AND BREASTFEEDING SAFETY: There are no adequate studies done on tizanidine to determine safe and effective use in pregnant women.
STORAGE: Store tizanidine tablets and capsules between temperatures of 15 C – 30 C (59 F – 86 F).
DOSAGE: Initially take 2 - 4 mg by mouth every 6 to 8 hours for up to 3 doses in 24 hours. Increase by 2 to 4 mg until satisfactory response is achieved; however, the maximum dose is 36 mg per day.
DRUG CLASS AND MECHANISM: Tizanidine is a skeletal muscle relaxant. It works on alpha2 receptors in the central nervous system (brain and spinal cord) and blocks nerve impulses from reaching muscles which produces muscle relaxation. The FDA approved tizanidine in November 1996.
Medically reviewed by Eni Williams, PharmD, PhD
REFERENCE: FDA Prescribing Information
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