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February 10, 2012
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tiopronin - oral, Thiola

GENERIC NAME: TIOPRONIN - ORAL (tie-oh-PRO-nin)

BRAND NAME(S): Thiola

Medication Uses | How To Use | Side Effects | Precautions | Drug Interactions | Overdose | Notes | Missed Dose | Storage

USES: This medication is used to prevent kidney stones in patients with a certain inherited disorder (cystinuria). Cystinuria occurs when there is too much of a certain natural substance (the amino acid cystine) in the urine, leading to formation of kidney stones. Tiopronin works by making cystine more dissolvable in the urine.This medication is usually used only after other methods are not successful in preventing kidney stones (e.g., drinking plenty of water, alkali therapy, special diet) or when patients cannot take the usual medication (d-penicillamine) for cystinuria.




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tiopronin - oral, Thiola

What is a kidney stone?

A kidney stone is a hard, crystalline mineral material formed within the kidney or urinary tract. Kidney stones are a common cause of blood in the urine (hematuria) and often severe pain in the abdomen, flank, or groin. Kidney stones are sometimes called renal calculi.

The condition of having kidney stones is termed nephrolithiasis. Having stones at any location in the urinary tract is referred to as urolithiasis, and the term ureterolithiasis is used to refer to stones located in the ureters.

Who is at risk for kidney stones?

Anyone may develop a kidney stone, but people with certain diseases and conditions (see below) or those who are taking certain medications are more susceptible to their development. It is estimated that one out of every 10 people in the U.S. will develop stones in the urinary tract at some point in their lives. Most urinary stones develop in peopl...

Read the Kidney Stones article »


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