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February 10, 2012
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tinzaparin - injection, Innohep

GENERIC NAME: TINZAPARIN - INJECTION (tin-ZAP-uh-rin)

BRAND NAME(S): Innohep

Warning | Medication Uses | How To Use | Side Effects | Precautions | Drug Interactions | Overdose | Notes | Missed Dose | Storage

WARNING: Tell your doctor if you use/have used tinzaparin before having any procedures involving puncture of the spine or needles left in the spine to give pain-blocking medication (including lumbar punctures, indwelling spinal/epidural catheters). Also, before starting tinzaparin, tell your doctor if you have had any of these procedures. Using this medication before/after these procedures has rarely caused severe bruising/bleeding in the area of the spine (epidural/spinal hematoma). This effect may cause paralysis that may be permanent. Discuss the risks and benefits of treatment with your doctor. Tell your doctor immediately if you have any of these serious side effects: back pain, tingling, weakness, numbness, or difficulty urinating. (See also Precautions section.)

This risk is increased the longer the needles are left in the spine or the more often these spinal puncture procedures are done. Using other "blood-thinning" or anti-platelet medications such as aspirin, clopidogrel, or warfarin, or nonsteroidal anti-inflammatory drugs (NSAIDs) such as ibuprofen or naproxen, also increases the risk. Do not stop taking any prescribed medication without first consulting your doctor. Your doctor will monitor you closely while you are using this medication.




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Introduction to deep vein thrombosis (DVT)

Arteries have thin muscles within their walls to be able to withstand the pressure of the heart pumping blood to the far reaches of the body. Veins don't have a significant muscle lining, and there is nothing pumping blood back to the heart except physiology. Blood returns to the heart because the body's large muscles squeeze the veins as they contract in their normal activity of moving the body. The normal activities of moving the body returns the blood back to the heart.

There are two types of veins in the leg; superficial veins and deep veins. Superficial veins lie just below the skin and are easily seen on the surface. Deep veins, as their name implies, are located deep within the muscles of the leg. Blood flows from the superficial veins into the deep venous system through small perforator veins. Superficial and perforator veins have one-way valves within them that allow blood to flow only in the direc...

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