opium tincture

  • Pharmacy Author:
    Omudhome Ogbru, PharmD

    Dr. Ogbru received his Doctorate in Pharmacy from the University of the Pacific School of Pharmacy in 1995. He completed a Pharmacy Practice Residency at the University of Arizona/University Medical Center in 1996. He was a Professor of Pharmacy Practice and a Regional Clerkship Coordinator for the University of the Pacific School of Pharmacy from 1996-99.

  • Medical and Pharmacy Editor: Charles Patrick Davis, MD, PhD
    Charles Patrick Davis, MD, PhD

    Charles Patrick Davis, MD, PhD

    Dr. Charles "Pat" Davis, MD, PhD, is a board certified Emergency Medicine doctor who currently practices as a consultant and staff member for hospitals. He has a PhD in Microbiology (UT at Austin), and the MD (Univ. Texas Medical Branch, Galveston). He is a Clinical Professor (retired) in the Division of Emergency Medicine, UT Health Science Center at San Antonio, and has been the Chief of Emergency Medicine at UT Medical Branch and at UTHSCSA with over 250 publications.

woman with abdominal pain

What is tincture of opium-oral liquid, and how does it work (mechanism of action)?

Opium tincture is an oral liquid medication used to control diarrhea. Opium tincture contains morphine which is an opioid pain reliever. Opioids can reduce gastrointestinal motility, propulsion, secretions, and increase gastrointestinal muscle tone. These effects help in controlling diarrhea. Opium tincture is a controlled substance.

What brand names are available for tincture of opium-oral liquid?

N/A

Is tincture of opium-oral liquid available as a generic drug?

GENERIC AVAILABLE: Yes

Do I need a prescription for tincture of opium-oral liquid?

Yes

What are the side effects of tincture of opium-oral liquid?

Side effects of opium tincture are:

Respiratory depression and physical and psychological dependence also occur.

Quick GuideDigestive Disorders: Common Misconceptions

Digestive Disorders: Common Misconceptions

What is the dosage for tincture of opium-oral liquid?

  • Adults: Take 0.6 ml by mouth 4 times a day not to exceed 6 ml per day.
  • Children: Safe and effective use of opium tincture is not established in children.

Which drugs or supplements interact with tincture of opium-oral liquid?

Opium tincture should not be used with medications like naltrexone and buprenorphine because they increase sedation and lower beneficial effect of opium tincture.

Opium tincture contains morphine. Morphine should be avoided in patients treated with monoamine oxidase inhibitors (MAOI) due to enhance toxicity of morphine including confusion, high blood pressure, tremor, hyperactivity, coma, and death. Drugs in this class include isocarboxazid (Marplan), phenelzine (Nardil), tranylcypromine (Parnate), selegiline (Eldepryl), and procarbazine (Matulane), and linezolid (Zyvox). Morphine should not be administered within 14 days of stopping an MAOI.

Is tincture of opium-oral liquid safe to take if I'm pregnant or breastfeeding?

There are no adequate studies done on opium tincture to determine safe and effective use in pregnant women.

Opium tincture contains morphine. Morphine is excreted in breast milk; however, the American Academy of Pediatrics committee states that it is safe to use while breastfeeding.

What else should I know about tincture of opium-oral liquid?

What preparations of tincture of opium-oral liquid are available?

Opium tincture is odorless oral liquid containing 10 mg of anhydrous morphine per one ml.

How should I keep tincture of opium-oral liquid stored?

Store tincture of opium at room temperature between 68 F to 77 F (20 C to 25 C).

REFERENCE: Tincture of Opium Prescribing Information.

Quick GuideDigestive Disorders: Common Misconceptions

Digestive Disorders: Common Misconceptions

Subscribe to MedicineNet's General Health Newsletter

By clicking Submit, I agree to the MedicineNet's Terms & Conditions & Privacy Policy and understand that I may opt out of MedicineNet's subscriptions at any time.

FDA Logo

Report Problems to the Food and Drug Administration

You are encouraged to report negative side effects of prescription drugs to the FDA. Visit the FDA MedWatch website or call 1-800-FDA-1088.

Reviewed on 9/14/2015
References
REFERENCE: Tincture of Opium Prescribing Information.

Health Solutions From Our Sponsors