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- What is tigecycline, and how does it work (mechanism of action)?
- What brand names are available for tigecycline?
- Is tigecycline available as a generic drug?
- Do I need a prescription for tigecycline?
- What are the side effects of tigecycline?
- What is the dosage for tigecycline?
- Which drugs or supplements interact with tigecycline?
- Is tigecycline safe to take if I'm pregnant or breastfeeding?
- What else should I know about tigecycline?
What is tigecycline, and how does it work (mechanism of action)?
Tigecycline is an injectable antibiotic used for the treatment of infections caused by susceptible bacteria. Tigecycline is similar to tetracycline antibiotics and has activity against a large number of bacteria. Tigecycline binds to bacterial ribosomes which produce the cell's proteins. The binding prevents bacterial ribosomes from producing important proteins needed for bacterial growth and multiplication. Tigecycline prevents bacteria from multiplying, but it does not kill bacteria. Tigecycline was approved by the FDA in June 2005.
What brand names are available for tigecycline?
Is tigecycline available as a generic drug?
GENERIC AVAILABLE: No.
Do I need a prescription for tigecycline?
What are the side effects of tigecycline?
Other side effects include:
- pain at the injection site;
- swelling and irritation;
- increased or decreased heart rate; and
Tigecycline is similar to tetracycline antibiotics and therefore may have similar side effects such as increased sensitivity to sunlight. Tigecycline may cause permanent discoloration of teeth if used during tooth development (last half of pregnancy, infancy, and childhood to the age of 8 years). Like other antibiotics, tygecycline can alter normal bacteria in the colon and encourage overgrowth of some bacteria such as Clostridium difficile, which causes inflammation of the colon (pseudomembranous colitis). Patients who develop signs of pseudomembranous colitis after starting tigecycline (diarrhea, fever, abdominal pain, and possibly shock) should contact their physician immediately.
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