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November 23, 2009
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Ticks

Medical Author: Charles Davis, MD, PhD
Medical Editor: William C. Shiel Jr., MD, FACP, FACR

Lyme Disease on Rise

Medical Author: William C. Shiel Jr., MD, FACP, FACR

Lyme disease is a tick-borne illness that causes symptoms such as a bull's eye rash, fatigue, and even heart failure and facial paralysis.Lyme disease is caused by infection with a bacterium called a spirochete (Borrelia burgdorferi) and is transmitted to humans by infected ticks (Ixodes scapularis and I. Pacificus). Patients with early stage Lyme disease have a characteristic rash (erythema migrans) accompanied by nonspecific symptoms (for example, fever, malaise, fatigue, headache, myalgia, and arthralgia). Lyme disease can usually be treated successfully with standard antibiotics.

The U.S. Centers for Disease Control and Prevention (CDC) released the results of a six-year survey study of Lyme disease from 1992 to 1998. During this period, a total of 88,967 cases of Lyme disease were reported to CDC by 49 states and the District of Columbia, with the number of cases increasing from 9,896 in 1992 to 16,802 in 1998. The researchers concluded that the increase in reported cases is probably a result of both a true increase in incidence within known high-risk areas as well as more complete reporting as a result of enhanced Lyme disease surveillance. They noted that surveillance capabilities and public awareness of Lyme disease have increased during this period.

Researchers also note that Lyme disease remains underreported with an estimated seven to 12 cases for each reported case.

What are ticks?

Ticks are scientifically classified as Arachnida (which includes spiders). The fossil record suggests ticks have been around at least 90 million years. There are over 800 species of ticks throughout the world, but only two families of ticks, Ixodidae (hard ticks) and Argasidae (soft ticks), are known to transmit diseases or illness to humans. Hard ticks have a scutum, or hard plate, on their back while soft ticks do not.

Ticks have a complex life cycle that includes eggs, larvae, nymphs, and adult male and female ticks. The larvae, nymphs, and adults all need blood meals. Usually, the female adult (hard tick) is the one causing the most bites as males usually die after mating. Ticks do not jump or fly. They simply reach out with their legs and grab or crawl onto a host. Although some larvae have preferred hosts, most ticks in the nymph or adult phase will attach a get a blood meal from several different kinds of animals, including humans. Except for a few species of larval ticks, the immature phases (larvae, nymphs) usually are even less selective about where they get a blood meal and are known to bite snakes, amphibians, birds, and mammals. Larvae are very small (about 1/32 of an inch with six legs), while nymphs are about 1/16-1/8 inch with eight legs and adults about 3/16-1/4 inch with eight legs. The complex life cycles are described in the last Web citation below, and all of the Web citations include pictures of various species of ticks. Although ticks will die eventually if they do not get a blood meal, many species can survive a year or more without a blood meal. The hard ticks tend to attach and feed for hours to days. Disease transmission usually occurs near the end of a meal, as the tick becomes full of blood. It may take hours before a hard tick transmits pathogens. Soft ticks usually feed for less than one hour. Disease transmission can occur in less than a minute with soft ticks. The bite of some of these soft ticks produces intensely painful reactions.

Ticks are vectors (transmitters) of diseases for humans and animals. Ticks can transmit disease to many hosts; some cause economic harm such as Texas fever (bovine babeiosis) in cattle that can kill up to 90% of yearling cows. Ticks act as vectors when pathogens in their saliva and mouth secretions get into the host's skin and blood. Ticks were understood to be vectors of disease in the mid-1800s, and as investigative methods improved (microscopes, culture techniques, tissue staining). more information showed the wide variety of diseases that could be transmitted by ticks.

Picture of a tick
Picture of a tick

What are tick bite symptoms?

Unfortunately, the tick bite is usually painless and remains that way even after the tick stops the blood meal and falls off of the skin. Later, the bite site may develop itching, burning, redness, and rarely, localized intense pain (some soft tick bites) in some individuals. A few individuals may be sensitive or allergic to tick bites (tick saliva secretions) and develop rash, shortness of breath, swelling, numbness, or paralysis. However, the majority of individuals with tick bites develop no symptoms, and many do not remember getting bitten.

Some immediate symptoms that infrequently or rarely develop during or immediately after a tick bite may be fever, shortness of breath, weakness, vomiting, swelling, weakness or paralysis, headache, confusion, or palpitations. Individuals with these symptoms should be seen immediately by a doctor.



Next: What diseases do ticks transmit (act as vectors) to humans? »

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Ticks

What is West Nile virus?

West Nile encephalitis is an infection of the brain that is caused by a virus known as the West Nile virus. First identified in Uganda in 1937, the virus is commonly found in Africa, West Asia, and the Middle East. "Encephalitis" means inflammation of the brain. One of the causes of encephalitis is viral and bacterial infections, including viral infections transmitted by mosquitoes.

West Nile virus had not been previously reported in the U.S. prior to an outbreak in New York in September 1999. According to the U.S. Centers for Disease Control and Prevention (CDC), there were 4,261 cases of disease caused by the West Nile virus internationally in 2006; however, the CDC says case reports are understated and estimates that there were 42,000 cases, most of which were unreported.

West Nile virus also is called West Nile fever or West Nile encephalitis.

Where did the West Nile virus come from?

...

Read the West Nile Virus article »










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