Thymoma

  • Medical Author:
    Melissa Conrad Stöppler, MD

    Melissa Conrad Stöppler, MD, is a U.S. board-certified Anatomic Pathologist with subspecialty training in the fields of Experimental and Molecular Pathology. Dr. Stöppler's educational background includes a BA with Highest Distinction from the University of Virginia and an MD from the University of North Carolina. She completed residency training in Anatomic Pathology at Georgetown University followed by subspecialty fellowship training in molecular diagnostics and experimental pathology.

  • Medical Editor: Jay W. Marks, MD
    Jay W. Marks, MD

    Jay W. Marks, MD

    Jay W. Marks, MD, is a board-certified internist and gastroenterologist. He graduated from Yale University School of Medicine and trained in internal medicine and gastroenterology at UCLA/Cedars-Sinai Medical Center in Los Angeles.

Thymoma Symptom

Chest Pain

There are many causes of chest pain. A serious form of chest pain is angina, which is a symptom of heart disease and results from inadequate oxygen supply to the heart muscle. Angina can be caused by coronary artery disease or spasm of the coronary arteries. Chest pain can also be due to a heart attack (coronary occlusion), aortic aneurysm dissection, myocarditis, esophageal spasm, esophagitis, rib injury or disease, anxiety, and other important diseases.

Thymoma facts

  • A thymoma is a type of tumor or growth in the thymus gland. It can behave in a benign fashion and is said to be noninvasive. Less commonly, it can behave in a malignant or cancerous fashion and is said to be a malignant thymoma. A small percentage of thymomas are clearly malignant and are called thymic carcinomas (cancers). In general, thymic tumors are uncommon.
  • The thymus gland is present in the front of the space between the lungs called the anterior mediastinum and behind the upper sternum. The thymus gland is larger during puberty, but then normally becomes smaller in adulthood.
  • Thymomas are most frequently seen in people in the fourth and fifth decades of life.
  • There are no known risk factors that predispose a person to developing a thymoma.
  • Up to half of thymomas are asymptomatic, meaning they do not produce any symptoms or signs and are diagnosed when an imaging study of the chest is performed for another reason.
  • Chest pain, shortness of breath, and cough are common symptoms that patients experience when symptoms do occur.
  • Many patients with thymoma will have a so-called paraneoplastic syndrome. A paraneoplastic syndrome occurs preceding or concurrent with the discovery of a thymoma. These conditions accompany the cancer's development but are not a direct result of the disease as a lump or pain might be. They seem to be an indirect result of the cancer and may or may not improve with the treatment of the underlying disease. The most commonly associated condition with thymoma is myasthenia gravis, a disease of muscle. Twenty percent of patients with myasthenia gravis will be found to have a thymoma.
  • Thymomas are slow-growing tumors, and the prognosis is excellent when they are discovered in their early stages. Five-year survival for thymoma patients receiving modern treatment approaches 80%. Patients with the more rare form of the disease called thymic carcinomas have a more aggressive disease with five-year survival even with treatment of only about 40% on average.
  • Surgical removal is the mainstay of treatment. Chemotherapy and radiation therapy may be used in cases in which surgical treatment is not effective in removing the entire tumor or in particularly aggressive cases.
Medically Reviewed by a Doctor on 4/12/2017

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