Thrombocytopenia (Low Platelet Count) (cont.)
How is thrombocytopenia treated?
The treatment of thrombocytopenia is largely dependent upon the cause and the
severity of the condition.
Some situations may require specific or emergent treatments, whereas, others
can only be managed by occasional blood draws and monitoring of the platelet
levels.
In auto-immune thrombocytopenia or ITP, steroids can be
used to weaken the immune system in order to impair the attack on platelets. In
more severe cases, intravenous immunoglobulins (IVIG) or antibodies may also be
given to slow down the immune process. In refractory cases, splenectomy (removal of the spleen) may
be necessary.
If a drug is thought to be the cause of low platelet count, then it may be
discontinued by the supervising physician. In patients with HIT, it is very
important to remove and avoid the future use of any heparin products, including
low molecular weight heparin (Lovenox), immediately to prevent further immune
response against the platelets.
If TTP or HUS is diagnosed, the treatment may include plasma exchange or
plasmapheresis. In
cases with severe kidney failure, dialysis may be necessary.
In general, platelet transfusion is not necessary, unless an individual with
low platelets (less than 50,000) has an active bleeding or hemorrhage, or needs
a surgery or other invasive procedures. Sometimes, transfusion may be
recommended without any bleeding if the platelet count is less than 10,000.
In suspected cases of HIT or TTP, transfusion of platelets is generally not
recommended because the new platelets can potentially make the condition worse
and more prolonged.
Next: What are the complications of thrombocytopenia? »
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