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February 10, 2012
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thiazide w/spironolactone-oral

GENERIC NAME: THIAZIDE W/SPIRONOLACTONE - ORAL (THIGH-uh-zide WITH SPY-row-no-lack-tone)

Warning | Medication Uses | How To Use | Side Effects | Precautions | Drug Interactions | Overdose | Notes | Missed Dose | Storage | Medical Alert

WARNING: This medication can raise your body's potassium levels. This is more likely to occur in people with kidney problems, diabetes, in elderly patients, or if the patient is severely ill. Potassium levels must be closely monitored in people with any of these problems or illnesses. If not treated, high potassium levels can be fatal. If you develop any of the following symptoms, notify your doctor immediately: muscle weakness, irregular heartbeat.

USES: This drug is a diuretic or "water pill". It reduces the amount of water and sodium retained by the body. It is used to lower blood pressure and to treat edema (fluid retention).

HOW TO USE: Take this exactly as prescribed. Do not skip doses or increase the dose without your doctor's approval. Take with food or milk to minimize stomach upset. Because this drug may increase urination, avoid taking a dose late in the day.

SIDE EFFECTS: This drug may cause dizziness or blurred vision. Use caution engaging in activities requiring alertness. Watch for signs of dehydration such as dry mouth or thirst. You may experience nausea, vomiting, loss of appetite, fatigue, sleeplessness, or nasal congestion the first few days as your body adjusts to the medication. If these effects persist or become bothersome, inform your doctor. Because this drug changes your fluid balance, you may feel dizzy if you change from a lying to a standing position too rapidly. Avoid this by sitting up a few minutes before rising. Thiazide-containing diuretics increase sensitivity to sunlight. Notify your doctor if you develop: a skin rash, yellowing of the skin, deepening of the voice, sore throat, weakness, irregular pulse, change in amount of urine, persistent cough. If you notice other effects not listed above, contact your doctor or pharmacist.

PRECAUTIONS: Tell your doctor your medical history, especially of: gout, diabetes, liver problems. Tell your doctor if you are allergic to sulfa drugs. You may also be allergic to this medication. Thiazides can make you more prone to sunburn. Avoid prolonged sun exposure. Use a sunscreen and wear protective clothing. Alcohol may further lower your blood pressure. Ask your doctor about its use. This medication should be used during pregnancy only if clearly needed. Discuss the risks and benefits with your doctor. This medication passes into breast milk. Consult your doctor before breast-feeding.




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      • High blood pressure, also known as hypertension, is a repeatedly elevated blood pressure exceeding 140 over 90 mmHg -- a systolic pressure above 140 with a diastolic pressure above 90. There are two causes of high blood pressure, primary and secondary. Primary high blood pressure is much more common that secondary and its basic causes or underlying defects are not always known. It is known that a diet high in salt increases the risk for high blood pressure, as well as high cholesterol. Genetic factors are also a primary cause. Secondary high blood pressure is generally caused by another condition such as renal hypertension, tumors, and other conditions. Treatment for high blood pressure is generally lifestyle changes and if necessary, diet.
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thiazide w/spironolactone-oral

What is edema?

Edema is observable swelling from fluid accumulation in body tissues. Edema most commonly occurs in the feet and legs, where it is referred to as peripheral edema. The swelling is the result of the accumulation of excess fluid under the skin in the spaces within the tissues. All tissues of the body are made up of cells and connective tissues that hold the cells together. This connective tissue around the cells and blood vessels is known as the interstitium. Most of the body's fluids that are found outside of the cells are normally stored in two spaces; the blood vessels (as the "liquid" or serum portion of your blood) and the interstitial spaces (not within the cells). In various diseases, excess fluid can accumulate in either one or both of these compartments.

The body's organs have interstitial spaces where fluid can accumulate. An accumulation of fluid in the interstitial air spaces (alveoli) in the lungs occurs in a disorder called...

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