Thiazides (Diuretics)

  • Pharmacy Author:
    Eni Williams, PharmD, PhD

    Dr. Eni Williams graduated from Creighton University in 1988 with a B.S. degree in pharmacy and a Doctor of Pharmacy from Howard University in 1994. She also obtained a Ph.D. in Public Policy in 2009 at the University of Maryland, Baltimore County.

  • Medical and Pharmacy Editor: Jay W. Marks, MD
    Jay W. Marks, MD

    Jay W. Marks, MD

    Jay W. Marks, MD, is a board-certified internist and gastroenterologist. He graduated from Yale University School of Medicine and trained in internal medicine and gastroenterology at UCLA/Cedars-Sinai Medical Center in Los Angeles.

For what conditions are thiazide diuretics used?

Thiazide diuretics are used to treat high blood pressure and congestive heart failure as well as the accumulation of fluid and swelling (edema) of the body caused by conditions such as heart failure, cirrhosis, chronic kidney failure, corticosteroid medications, and nephrotic syndrome.

What are the side effects of thiazide diuretics?

Side effects of thiazide diuretics are dose related and include:

Other side effects and adverse reactions are:

  • An increased sensitivity to sunlight (prolonged sun exposure should be avoided)
  • Owing to their ability to increase the production of urine, these drugs may lower levels in the body of potassium and magnesium which also are present in urine.
  • Thiazide diuretics may increase uric acid levels in blood.
  • Like other antihypertensive medications, thiazides cause sexual dysfunction.

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