theophylline, Elixophyllin, Theo-24, (Theolair, Uniphyl Theo-Dur, and Slo-Phyllin-discontinued) (cont.)

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Medical and Pharmacy Editor:

Other important and more serious side effects include seizures and heart arrhythmias. Theophylline should be used cautiously in patients with high blood pressure, peptic ulcer disease, seizure disorders, and serious heart disease, especially heart rhythm problems.

PREPARATIONS: Capsule (extended release): 100, 200, 300, and 400 mg

DRUG INTERACTIONS: Certain groups of patients breakdown theophylline slowly, and can develop elevated blood levels and potential toxicity even on normal doses. These patients include those with liver disease, older men with chronic lung diseases, infants, patients with high fever or heart failure, and patients taking other medications that increase blood theophylline levels.

Examples of medications that can elevate theophylline blood levels include ephedrine, allopurinol (Zyloprim), cimetidine (Tagamet), ciprofloxacin (Cipro), clarithromycin (Biaxin), itraconazole (Sporanox), ketoconazole, erythromycin, oral contraceptives, fluvoxamine (Luvox), and propranolol (Inderal).

Medically Reviewed by a Doctor on 1/5/2016


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