thalidomide, Thalomid

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GENERIC NAME: thalidomide

BRAND NAME: Thalomid

DRUG CLASS AND MECHANISM: Thalidomide is an oral medication used for treating the skin conditions of leprosy, a disease caused by a parasite, Mycobacterium leprae. The mechanism of action of thalidomide is not well understood. The immune system reaction to Mycobacterium leprae plays an important role in producaing the skin manifestations of leprosy. Scientists believe that thalidomide modifies the reaction of the immune system to Mycobacterium leprae and thereby suppresses the skin reaction. Thalidomide also is being evaluated as a treatment for HIV and several other conditions. Thalidomide was approved by the FDA in July 1998.

PRESCRIBED FOR: Thalidomide is used for the treatment and prevention of skin conditions resulting from leprosy (erythema nodosum leprosum) and for treating multiple myelomas. Thalidomide has also been used off-label for treating mycobacterium tuberculosis (TB), aphthous ulcers, HIV-wasting syndrome, Crohn's disease, and Kaposi's sarcoma.

Medically Reviewed by a Doctor on 7/24/2015



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