tetanus - toxoid injection (Tetanus Toxoid Adsorbed)

  • Pharmacy Author:
    Omudhome Ogbru, PharmD

    Dr. Ogbru received his Doctorate in Pharmacy from the University of the Pacific School of Pharmacy in 1995. He completed a Pharmacy Practice Residency at the University of Arizona/University Medical Center in 1996. He was a Professor of Pharmacy Practice and a Regional Clerkship Coordinator for the University of the Pacific School of Pharmacy from 1996-99.

  • Medical and Pharmacy Editor: Charles Patrick Davis, MD, PhD
    Charles Patrick Davis, MD, PhD

    Charles Patrick Davis, MD, PhD

    Dr. Charles "Pat" Davis, MD, PhD, is a board certified Emergency Medicine doctor who currently practices as a consultant and staff member for hospitals. He has a PhD in Microbiology (UT at Austin), and the MD (Univ. Texas Medical Branch, Galveston). He is a Clinical Professor (retired) in the Division of Emergency Medicine, UT Health Science Center at San Antonio, and has been the Chief of Emergency Medicine at UT Medical Branch and at UTHSCSA with over 250 publications.

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Rare but serious side effects include:

Rare cases of anaphylactic shock have been reported after receiving some preparations containing the tetanus toxoid.



PREPARATIONS: Vial: 0.5 ml unit dose & 5 ml vial

STORAGE: Tetanus toxoid vaccines should be refrigerated between 2.2 C and 7.7 C (36 F and 46 F). Do not freeze.

DOSING: The recommended dose is 0.5 ml injected intramuscularly. Repeat at 4 to 8 weeks after the first dose and at 6 to 12 months after the second dose.


Some medications may decrease the therapeutic benefits of the tetanus toxoid vaccine. Example of such medications include:

PREGNANCY: Tetanus toxoid is classified as FDA pregnancy risk category C. Animal reproduction studies have shown an adverse effect on the fetus and there are no adequate and well-controlled studies in humans, but potential benefits may warrant use of the drug in pregnant women despite potential risks. Adequate and well-controlled studies of the tetanus toxoid vaccine in pregnant women are lacking.

NURSING MOTHERS: It is not known if tetanus toxoid is excreted in breast milk.

REFERENCE: FDA Prescribing Information.

Medically Reviewed by a Doctor on 12/22/2014

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