tetanus - toxoid injection (Tetanus Toxoid Adsorbed)

  • Pharmacy Author:
    Omudhome Ogbru, PharmD

    Dr. Ogbru received his Doctorate in Pharmacy from the University of the Pacific School of Pharmacy in 1995. He completed a Pharmacy Practice Residency at the University of Arizona/University Medical Center in 1996. He was a Professor of Pharmacy Practice and a Regional Clerkship Coordinator for the University of the Pacific School of Pharmacy from 1996-99.

  • Medical and Pharmacy Editor: Charles Patrick Davis, MD, PhD
    Charles Patrick Davis, MD, PhD

    Charles Patrick Davis, MD, PhD

    Dr. Charles "Pat" Davis, MD, PhD, is a board certified Emergency Medicine doctor who currently practices as a consultant and staff member for hospitals. He has a PhD in Microbiology (UT at Austin), and the MD (Univ. Texas Medical Branch, Galveston). He is a Clinical Professor (retired) in the Division of Emergency Medicine, UT Health Science Center at San Antonio, and has been the Chief of Emergency Medicine at UT Medical Branch and at UTHSCSA with over 250 publications.

GENERIC NAME: tetanus toxoid

BRAND NAME: Tetanus Toxoid Adsorbed

DRUG CLASS AND MECHANISM: Tetanus toxoid is a vaccine used to provide active immunity against tetanus toxin. Tetanus or lockjaw is a serious disease that may result in death. Tetanus toxin causes tightening of the muscles all over the body, and can lead to the locking of the jaw which prevents the victim from opening their mouth or swallowing. Tetanus is caused by the Clostridium tetani (C.tetani) bacteria that secrete the toxin. C.tetani usually enters the body through open wounds. The tetanus vaccination is widely available and is highly effective in preventing this potentially deadly disease.

Since our bodies do not naturally produce antibodies against the tetanus toxin, primary vaccination and booster shots given every 10 years are recommended to protect individuals of all ages. Vaccines contain antigens that induce the production of antibodies against the toxin produced by C. tetani infections.

Tetanus toxoid vaccines are not intended to treat active tetanus infections. Active tetanus infections may be treated with the tetanus immune globulin. However, patients must receive the tetanus toxoid vaccine after the infection has been adequately treated.

PRESCRIBED FOR: The tetanus toxoid vaccine is used for active immunization against tetanus in individuals 7 years of age and older.

SIDE EFFECTS: All vaccines may cause minor injection site reactions including:

  • Pain
  • Redness
  • Swelling (edema)
  • Warmth
  • Discomfort

Some individuals also may experience:

Medically Reviewed by a Doctor on 12/22/2014

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