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The Cleveland Clinic

Erectile Dysfunction: Testosterone Replacement Therapy

Testosterone is a hormone produced by the testicles and is responsible for the proper development of male sexual characteristics. Testosterone is also important for maintaining muscle bulk, adequate levels of red blood cells, bone growth, sense of well-being and sexual function.

Inadequate production of testosterone is not a common cause of erectile dysfunction; however, when ED does occur due to decreased testosterone production, testosterone replacement therapy may improve the problem.

What Causes Testosterone Deficiency?

As a man ages, the amount of testosterone in his body gradually declines. This natural decline starts after age 30 and continues throughout life. Other causes of lowered testosterone levels include:

  • Injury or infection to the testicles
  • Chemotherapy or radiation treatment for cancer
  • Genetic abnormalities such as Klinefelter's Syndrome (extra X chromosome)
  • Hemochromatosis (too much iron in the body)
  • Dysfunction of the pituitary gland (a gland in the brain that produces many important hormones)
  • Inflammatory diseases such as sarcoidosis (a condition that causes inflammation of the lungs)
  • Medications, especially hormones used to treat prostate cancer and corticosteroid drugs
  • Chronic illness
  • Chronic kidney failure
  • Liver cirrhosis
  • Stress
  • Alcoholism

The significance of testosterone decline is controversial and poorly understood.



Next: What are the symptoms of testosterone deficiency? »

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  • testosterone gel-topical, Androgel, Testim - Consumer information about the medication TESTOSTERONE GEL - TOPICAL (Androgel, Testim), includes side effects, drug interactions, recommended dosages, and storage information. Read more about the prescription drug TESTOSTERONE GEL - TOPICAL.
  • Erectile Dysfunction (Impotence) - Read about erectile dysfunction (ED) / impotence includes what it is, how ED is diagnosed, and treatment options.
  • testosterone-transdermal, Androderm, Testoderm TTS - Consumer information about the medication TESTOSTERONE - TRANSDERMAL (Androderm, Testoderm TTS), includes side effects, drug interactions, recommended dosages, and storage information. Read more about the prescription drug TESTOSTERONE - TRANSDERMAL.

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Testosterone Therapy to Treat ED

What is the most common cause of sex problems among couples?

While they can take many forms, sex problems are defined as any physical or emotional issue that prevents a couple from achieving a mutually satisfying intimate relationship. Among the most common for men include prostate problems, a decrease in the blood supply to the penis due to diabetes, heart disease or other health concerns, nerve damage to the spinal cord, or a decrease in the hormone testosterone. In women common problems include a lack of desire caused by a decrease in the hormone estrogen, thyroid disorders (which can also affect some men), and pain during intercourse caused by any number of vaginal problems, including a lack of lubrication.

Some couples also find that the use of certain drugs can also cause sexual problems. These include alcohol, nicotine, narcotics, stimulants, some blood pressure drugs, antihistamines, and certa...

Read the Sexual Health: FAQs About Sex and Relationships article »










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