testosterone gel (Androgel) (cont.)
Omudhome Ogbru, PharmD
Omudhome Ogbru, PharmD
Dr. Ogbru received his Doctorate in Pharmacy from the University of the Pacific School of Pharmacy in 1995. He completed a Pharmacy Practice Residency at the University of Arizona/University Medical Center in 1996. He was a Professor of Pharmacy Practice and a Regional Clerkship Coordinator for the University of the Pacific School of Pharmacy from 1996-99.
Medical and Pharmacy Editor:
GENERIC AVAILABLE: No
PREPARATIONS: 1% Solution: 25 mg/2.5 g, 50 mg/5 g, 1.25 g/Actuation
STORAGE: Androgel should be stored at room temperature 15 C to 30 C (59 F to 86 F)
PRESCRIBED FOR: Androgel is a testosterone replacement product used for men 18 years old or older with a deficiency or absence of testosterone due to primary hypogonadism or hypogonadotropic hypogonadism.
DOSING: The recommended starting dose is 50 mg applied once daily to the skin of shoulders, upper arm, or abdomen. The dose may be increased based on blood testosterone levels. The hands should be washed thoroughly with soap and water after applying Androgel.
DRUG INTERACTIONS: Testosterone may decrease blood glucose levels. Therefore, less insulin may be required in diabetic patients. Testosterone may increase the action of the blood thinner warfarin (Coumadin), increasing the risk of bleeding. Combining steroids with testosterone may increase fluid retention.
PREGNANCY: Androgel should not be used during pregnancy because testosterone is harmful to the fetus.
NURSING MOTHERS: Androgel should not be used by nursing mothers because of the possibility of adverse effects in the nursing infant.
SIDE EFFECTS: The most common side effects of Androgel are headache, high blood pressure, acne, abnormal lab tests (for example, glucose and cholesterol tests), application site reactions (for example, itching, blisters, and redness), enlarged prostate, and increased serum prostate specific antigen (PSA) levels.
REFERENCE: FDA Prescribing Information.
Last Editorial Review: 11/16/2012
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