teriflunomide (Aubagio)

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GENERIC NAME: teriflunomide


DRUG CLASS AND MECHANISM: Teriflunomide is an oral immunomodulatory agent used for the treatment of patients with relapsing forms of multiple sclerosis (MS). It inhibits dihydroorotate dehydrogenase, an enzyme used to make pyrimidine which is used to build DNA. The exact mechanism of action of teriflunomide in the treatment of MS is unknown. However, it is thought to reduce the over activation of the immune system by decreasing the number of white blood cells (T and B lymphocytes) in the central nervous system. Teriflunomide decreases the number of MS relapses. The FDA approved teriflunomide in September 2013.



PREPARATIONS: Film-coated tablets: 7 mg and 14 mg

STORAGE: Tablets should to be stored at 20 C to 25 C (68 F to 77 F), but also may be stored at 15 C to 30 C (59 F to 86 F)

Medically Reviewed by a Doctor on 8/19/2014

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