terconazole, Terazol, Zazole
Omudhome Ogbru, PharmD
Omudhome Ogbru, PharmD
Dr. Ogbru received his Doctorate in Pharmacy from the University of the Pacific School of Pharmacy in 1995. He completed a Pharmacy Practice Residency at the University of Arizona/University Medical Center in 1996. He was a Professor of Pharmacy Practice and a Regional Clerkship Coordinator for the University of the Pacific School of Pharmacy from 1996-99.
Medical and Pharmacy Editor:
GENERIC NAME: terconazole
BRAND NAME: Terazol, Zazole
DRUG CLASS AND MECHANISM: Terconazole is an anti-fungal cream and suppository used for treating vaginal yeast infections (Candida). It is related to several other anti-fungal drugs including fluconazole (Diflucan), ketoconazole (Nizoral), itraconazole (Sporanox), miconazole (Micatin, Monistat), and clotrimazole (Lotrimin). It prevents growth of yeast by preventing production of the membranes that surround the yeast cells. The FDA approved terconazole in December 1987.
GENERIC AVAILABLE: Yes
PREPARATIONS: Vaginal cream: 0.4 and 0.8%. Vaginal suppositories: 80 mg.
STORAGE: Terconazole should be stored at room temperature 15-30 C (59-86 F).
PRESCRIBED FOR: Terconazole is used for the treatment of vaginal infections caused by yeast.
DOSING: One applicator full of the 0.4% vaginal cream should be applied into the vagina at bedtime for 7 days. One applicator full of the 0.8% vaginal cream or one vaginal suppository should be applied at bedtime for 3 days.
DRUG INTERACTIONS: There are no known drug interactions with topical terconazole.
PREGNANCY: There are no adequate studies in pregnant women.
NURSING MOTHERS: It is not known if terconazole is secreted in breast milk.
SIDE EFFECTS: The most common side effects associated with terconazole are irritation, increased sensitivity and burning of the vulvae or vagina. Other side effects include headache, painful menstrual periods, aches, abdominal pain, fever, chills, and itching.
Reference: FDA Prescribing Information
Last Editorial Review: 3/27/2009
Report Problems to the Food and Drug Administration
You are encouraged to report negative side effects of prescription drugs to the FDA. Visit the FDA MedWatch website or call 1-800-FDA-1088.
Need help identifying pills and medications?
Back to Medications Index