Medications and Drugs
Pharmacy Author: Omudhome Ogbru, PharmD
Medical and Pharmacy Editor: Jay W. Marks, MD
GENERIC NAME: terconazole
BRAND NAME: Terazol, Zazole
DRUG CLASS AND MECHANISM: Terconazole is an anti-fungal cream and suppository
used for treating vaginal yeast infections (Candida). It is related to several
other anti-fungal drugs including fluconazole (Diflucan), ketoconazole
(Nizoral), itraconazole (Sporanox), miconazole (Micatin, Monistat), and
clotrimazole (Lotrimin). It prevents growth of yeast by preventing production of
the membranes that surround the yeast cells. The FDA approved terconazole in
December 1987.
PRESCRIPTION: Yes
GENERIC AVAILABLE: Yes
PREPARATIONS: Vaginal cream: 0.4 and 0.8%. Vaginal suppositories: 80
mg.
STORAGE: Terconazole should be stored at room temperature 15-30 C
(59-86 F).
PRESCRIBED FOR: Terconazole is used for the treatment of vaginal
infections caused by yeast.
DOSING: One applicator full of the 0.4% vaginal cream should be
applied into the vagina at bedtime for 7 days. One applicator full of the 0.8%
vaginal cream or one vaginal suppository should be applied at bedtime for 3
days.
DRUG INTERACTIONS: There are no known drug interactions with topical
terconazole.
PREGNANCY: There are no adequate studies in
pregnant women.
NURSING MOTHERS: It is not known if terconazole is secreted in
breast
milk.
SIDE EFFECTS: The most common side effects associated with terconazole
are irritation, increased sensitivity and
burning of the vulvae or vagina. Other
side effects include headache,
painful menstrual periods, aches, abdominal pain,
fever,
chills, and itching.
Reference: FDA Prescribing Information
Last Editorial Review: 3/27/2009
Report Problems to the Food and Drug Administration
You are encouraged to report negative side effects of prescription drugs to the FDA. Visit the FDA MedWatch website or call 1-800-FDA-1088.
- Drug Interactions - Learn about potential drug interactions you may be exposed to. Drug interactions can occur with prescription drugs, OTC medication, vitamins, herbs, and supplements.
- Yeast Infection - Learn about vaginal yeast infection symptoms like vaginal burning, itching, soreness discharge, and pain during sex and urination. Treatment information is included in the information.
- ketoconazole, Nizoral, Extina, Xolegel, Kuric - Learn about ketoconazole (Nizoral, Extina, Xolegel, Kuric), a drug used to treat a variety of fungal infections such as dandruff, jock itch, athlete's foot, and ringworm.
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