terbinafine, Lamisil, Lamisil AT

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GENERIC NAME: terbinafine

BRAND NAME: Lamisil, Lamisil AT

DRUG CLASS AND MECHANISM: Terbinafine is an antifungal agent that is taken by mouth or applied to the skin. Terbinafine acts by interfering with the ability of fungi to make chemicals called sterols that are an important part of the membrane that surrounds fungal cells and holds them together. This weakens the cell membrane. Oral terbinafine is more effective for treating fungal nail infections than griseofulvin (Fulvicin; Gris-Peg) and itraconazole (Sporanox), two other antifungal agents used for treating fungal nail infections. Topical terbinafine was approved by the FDA in 1993. Terbinafine oral tablets were approved in 1996.

PRESCRIPTION: Yes (Tablets), OTC (Topical preparations)

GENERIC AVAILABLE: Yes

PREPARATIONS: Tablets: 250 mg. Oral Granule: 125 and 187.5 mg. Cream, Gel, solution, or spray: 1%.

STORAGE: All formulations should be stored at room temperature, 15-30 C (59-86 F).

PRESCRIBED FOR:

  • Tablets: Fungal infections of the toe, or fingernail, caused by the fungus, tinea unguium.
  • Topical formulations (cream, gel, spray, solution): Fungal infections of the skin including tinea pedis (athlete's foot), tinea corporis (ringworm), and tinea cruris (jock itch).



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