terazosin, Hytrin

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GENERIC NAME: terazosin


DRUG CLASS AND MECHANISM: Terazosin belongs to a class of medications called alpha 1 blockers which relax the smooth muscles of the arteries, the prostate, and the bladder neck. Other alpha blockers include doxazosin (Cardura), alfuzosin (Uroxatral), tamsulosin (Flomax), and prazosin (Minipress). Relaxing the smooth muscles of the arteries lowers blood pressure. Relaxing the smooth muscles around the bladder neck relieves urinary obstruction caused by an enlarged prostate (prostate hypertrophy). Terazosin relaxes the smooth muscles of the bladder neck and the prostate, increasing urine flow. The FDA approved terazosin in 1987.



PREPARATIONS: Tablets or Capsules: 1, 2, 5, and 10 mg.

STORAGE: Terazosin should be stored at room temperature below 86 F (30 C) in a tight container.

PRESCRIBED FOR: Terazosin is used to treat the symptoms of urinary obstruction due to an enlarged prostate caused by benign prostatic hypertrophy (BPH). Terazosin also is used alone or in combination with another blood pressure medication to treat high blood pressure.

DOSING: Terazosin may be taken with or without food. The recommended starting dose for treating BPH is 1 mg daily. The dose should be increased in a stepwise fashion up to 10 mg daily which is the effective dose for most patients. Some patients may show additional improvement with a 20 mg dose. For high blood pressure the recommended dose is 1 to 5 mg once daily. Some patients may benefit from doses as high as 20 mg per day. Terazosin also may be administered twice daily.

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