tenofovir-oral (cont.)
SIDE EFFECTS: See also Warning section. Nausea, vomiting, diarrhea, headache, dizziness, stomach upset, sweating, muscle pain, or gas may occur. If any of these effects persist or worsen, contact your doctor or pharmacist promptly. Tell your doctor immediately if any of these serious side effects occur: loss of appetite, depression, chest pain, numbness or tingling of the hands or feet, change in the amount of urine, unusual weight loss, unusual tiredness or weakness. Changes in body fat may occur while you are taking this medication (e.g., increased fat in the upper back and stomach areas, decreased fat in the arms and legs). The cause and long-term effects of these changes are unknown. Discuss the risks and benefits of therapy with your doctor, as well as the possible role of exercise to reduce this side effect. A serious allergic reaction to this drug is unlikely, but seek immediate medical attention if it occurs. Symptoms of a serious allergic reaction include: rash, itching, swelling, severe dizziness, trouble breathing. If you notice other effects not listed above, contact your doctor or pharmacist.
PRECAUTIONS: Tell your doctor your medical history, especially of: kidney problems, liver disease, bone problems, any allergies. Caution is advised when using this drug in the elderly because they may be more sensitive to the effects of the drug. Tell your doctor if you are pregnant before using this medication. It is not known if this medication passes into breast milk. Because breast-milk can transmit HIV, do not breast-feed.
DRUG INTERACTIONS: Tell your doctor of all prescription and nonprescription medication you may use, especially: certain other HIV medicines (e.g., didanosine), other antiviral medicines (e.g., acyclovir, cidofovir, ganciclovir, lamivudine and abacavir). Also report the use of other drugs which might be potentially toxic to the kidney such as: aminoglycosides (e.g., gentamicin, amikacin), amphotericin B, cyclosporine, non-steroidal anti-inflammatory drugs - NSAIDS (e.g., ibuprofen), tacrolimus, vancomycin. Tenofovir can decrease the effectiveness of atazanavir (by decreased blood levels) when the two drugs are given in combination. This can result in a worsening of your condition. According to the manufacturer, adding ritonavir to the combination of atazanavir and tenofovir may be a treatment option. Consult your doctor or pharmacist for more details. Do not start or stop any medicine without doctor or pharmacist approval.
Report Problems to the Food and Drug Administration
You are encouraged to report negative side effects of prescription drugs to the FDA. Visit the FDA MedWatch website or call 1-800-FDA-1088.
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