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temozolomide-oral (cont.)

PRECAUTIONS: Tell your doctor your medical history, especially of: kidney disease, liver disease, blood disorders (e.g., neutropenia, thrombocytopenia), allergies (especially to dacarbazine). This medication can lower the body's ability to fight an infection. Notify your doctor promptly if you develop any signs of an infection such as fever, chills or persistent sore throat. Use this medication with caution in the elderly because they may be more sensitive to the effects of the drug. Use this medication with caution in women because they may be more sensitive to the effects of the drug. This medication is not recommended for use during pregnancy. Consult your doctor for more details. Men and women should use effective birth control while using this medication. Consult your doctor or pharmacist for more information. It is not known if this drug passes into breast milk. Due to the potential risk to the infant, breast-feeding while using this drug is not recommended. Consult your doctor before breast- feeding.

DRUG INTERACTIONS: Tell your doctor of all prescription and nonprescription medication you may use. Do not start or stop any medicine without doctor or pharmacist approval.

OVERDOSE: If overdose is suspected, contact your local poison control center or emergency room immediately. US residents can call the US national poison hotline at 1-800-222-1222. Canadian residents should call their local poison control center directly. Symptoms of overdose may include chills, persistent sore throat or fever; or easy bleeding or bruising.

NOTES: Do not share this medication with others. Laboratory and/or medical tests (e.g., blood tests, brain scans) may be performed to monitor your progress. Keep all scheduled medical appointments.

MISSED DOSE: If you miss a dose, contact your doctor or healthcare provider immediately to establish a new dosing schedule.

STORAGE: Store at room temperature below 77 degrees F (25 degrees C) away from light and moisture.


Last Editorial Review: 3/2/2005




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