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November 24, 2009
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GENERIC NAME: TEMOZOLOMIDE - ORAL (temm-oh-ZOH-loh-mide)

BRAND NAME(S): Temodar

Medication Uses | How To Use | Side Effects | Precautions | Drug Interactions | Overdose | Notes | Missed Dose | Storage

USES: This medication is used to treat certain types of brain cancers (e.g., refractory anaplastic astrocytoma).

HOW TO USE: Take this medication by mouth, generally once daily for five consecutive days per 28-day treatment cycle; or take as directed by your doctor. Dosage is based on your size and response to therapy. Consult your doctor or pharmacist if you are not certain which days of the cycle to take your medication. Take this medication on an empty stomach (one hour before or three hours after a meal) or at bedtime, unless otherwise directed by your doctor. Swallow the capsules (medication) whole with a full glass of water (8oz. or 240mL). Do not crush or chew the capsules. If you vomit within 30 minutes of taking this medication, notify your doctor immediately. If you vomit before taking this medication, your doctor may be able to prescribe anti-nausea medication for you to take before therapy begins. Consult your doctor. Do not open the capsules (medication). If capsules are accidentally opened or damaged, avoid inhalation or contact of the medication with skin or mucous membranes (e.g., inside the nose). Take all other medication (e.g., anti-nausea drugs) exactly as prescribed by your doctor.

SIDE EFFECTS: Nausea, tiredness, constipation and headache may occur. If any of these effects persist or worsen, notify your doctor promptly. Tell your doctor immediately if you have any of these serious side effects: unusual dizziness or drowsiness, easy bleeding or bruising, persistent sore throat, fever, seizures, unusual weakness, loss of coordination, mental/mood changes, vision changes, swelling, rash, diarrhea, trouble sleeping. If you notice other effects not listed above, contact your doctor or pharmacist.




Report Problems to the Food and Drug Administration

 

You are encouraged to report negative side effects of prescription drugs to the FDA. Visit the FDA MedWatch website or call 1-800-FDA-1088.


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