GENERIC NAME: telmisartan

BRAND NAME: Micardis

DRUG CLASS AND MECHANISM: Telmisartan is a member of a family of drugs called angiotensin receptor blockers (ARBs), which includes losartan (Cozaar), valsartan (Diovan), irbesartan (Avapro), and candesartan (Atacand). ARBs block the ability of the chemical angiotensin II to constrict or squeeze arteries and veins. As a result, the arteries and veins enlarge and blood pressure falls. The reduced pressure in the arteries also makes it easier for the heart to pump blood. Telmisartan was approved by the FDA in November of 2000.

PRESCRIPTION: Yes

GENERIC AVAILABLE: No

PREPARATIONS: Tablets of 40 mg and 80 mg.

STORAGE: Telmisartan should be stored at room temperature, 15-30°C (59-86°F). The tablets should be kept in their blister-pack packaging until they are used.

PRESCRIBED FOR: Telmisartan is used for the treatment of hypertension (high blood pressure).

DOSING: Telmisartan is taken once daily with or without food.

DRUG INTERACTIONS: Telmisartan can increase blood concentrations of digoxin.

PREGNANCY: Medications which interfere with the angiotensin converting enzyme system, such as telmisartan, have been found to cause fetal and neonatal toxicity and death when taken by pregnant women. Pregnant mothers should discontinue use of telmisartan as soon as they know they are pregnant.

NURSING MOTHERS: It is not known if telmisartan is secreted into breast milk. Since most medicines are secreted into breast milk, potential risks and benefits need to be assessed in women who are nursing to determine if breast feeding or telmisartan need to be discontinued.

SIDE EFFECTS: Like other angiotensin receptor blockers, telmisartan generally is well-tolerated. The most common side effects have been headache (1 in 10 patients), dizziness (1 in 25), back pain (1 in 30), fatigue (1 in 30), and diarrhea (1 in 30).

Pharmacy Author: Emmanuel Saltiel, Pharm.D.
Pharmacy Editor: Jay Marks, M.D.

Last Editorial Review: 1/22/2002 7:41:00 PM

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